Dept. of Otolaryngology, Faculty of Medicine, Baskent University, Ankara, Turkey.
Dept. of Otolaryngology, Faculty of Medicine, Baskent University, Ankara, Turkey.
Int J Pediatr Otorhinolaryngol. 2021 Aug;147:110777. doi: 10.1016/j.ijporl.2021.110777. Epub 2021 May 21.
This study aimed to compare the integrity of the efferent auditory pathways of newborns that had high hyperbilirubinemia levels and required treatment due to these and healthy newborns.
Term-born (37 weeks or later) infants that were brought to the Newborn Polyclinic of the Başkent University Hospital were included in the study. The study included a total of 84 infants including healthy newborns (n = 42) and those that had jaundice and were receiving phototherapy (n = 42). After conducting a general otorhinolaryngology examination on all newborns included in the study, Transient Otoacoustic Emission (TEOAE) test was carried out in the absence and presence of contralateral noise. The obtained contralateral suppression values were compared between the two groups.
In the TEOAE test, the responses obtained at 1 kHz in the newborns receiving phototherapy were found to be lower. The difference between the groups was significant (p = 0.038). The rates of suppression presence at 2 kHz, 2.8 kHz and total OAE were found significantly higher (p < 0.05) in the group not receiving phototherapy. Among the phototherapy-receiving infants, the hyperbilirubinemia levels of the infants in whom suppression was obtained in the contralateral suppression test did not show a statistically significant difference in comparison to those in whom suppression was not obtained (p > 0.05).
Based on the obtained data, hyperbilirubinemia may have a disruptive effect on the efferent auditory system in newborns. Consequently, we are of the opinion that, in addition to hearing screening in risky newborn infants, a MOC suppression test would be useful.
本研究旨在比较高胆红素血症水平并因此需要治疗的新生儿与健康新生儿的传出听觉通路完整性。
本研究纳入了来自 Başkent 大学医院新生儿综合诊所的足月(37 周或以上)新生儿。研究共纳入 84 例新生儿,包括健康新生儿(n=42)和接受光疗的黄疸新生儿(n=42)。对所有纳入研究的新生儿进行一般耳鼻喉科检查后,在无和有对侧噪声的情况下进行瞬态耳声发射(TEOAE)测试。比较两组的对侧抑制值。
在 TEOAE 测试中,接受光疗的新生儿在 1 kHz 处获得的反应较低。两组之间的差异具有统计学意义(p=0.038)。未接受光疗组在 2 kHz、2.8 kHz 和总 OAE 处的抑制存在率显著更高(p<0.05)。在接受光疗的婴儿中,在对侧抑制测试中获得抑制的婴儿的高胆红素血症水平与未获得抑制的婴儿相比没有统计学差异(p>0.05)。
基于获得的数据,高胆红素血症可能对新生儿的传出听觉系统有破坏作用。因此,我们认为,除了对高危新生儿进行听力筛查外,MOC 抑制测试也将是有用的。