Thompson I M, Peek M
Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, Texas.
J Urol. 1988 Sep;140(3):487-90. doi: 10.1016/s0022-5347(17)41698-3.
A review of 212 cases of renal cell carcinoma diagnosed during a 40-year period revealed an increasing number of cases detected during imaging studies performed for nonurological reasons. These so-called incidentally detected renal cell carcinomas are increasing in incidence, generally of low stage and associated with significantly improved survival, and they constitute the majority of the patients with improved prognosis during the recent 2 decades. The clinical course and disease stage in patients who continue to present with symptoms of the disease have not changed in the last 40 years. These data suggest that with currently available treatments for renal cell carcinoma a principal method to improve the prognosis of this disease would be through earlier detection. Low disease incidence would mitigate against morphological screening but case finding techniques may prove useful.
一项对40年间确诊的212例肾细胞癌病例的回顾显示，在因非泌尿系统原因进行的影像学检查中发现的病例数量不断增加。这些所谓的偶然发现的肾细胞癌发病率在上升，通常分期较低，生存率显著提高，并且在最近20年中构成了预后改善患者的大多数。在过去40年中，持续出现疾病症状的患者的临床病程和疾病分期没有变化。这些数据表明，对于目前可用的肾细胞癌治疗方法，改善该疾病预后的主要方法将是早期检测。低发病率不利于形态学筛查，但病例发现技术可能证明是有用的。
