Department of Geriatric Medicine, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
Department of Clinical Medicine, Aalborg University, DK-9000 Aalborg, Denmark.
Age Ageing. 2021 Nov 10;50(6):1914-1924. doi: 10.1093/ageing/afab105.
falls among older adults are common and can have devastating consequences. A novel task-specific exercise modality, gait adaptability training (GAT), has shown promising preventive effects. This systematic review and meta-analysis synthesise the evidence regarding GATs effect on falls and fall-related fractures in community-dwelling older adults.
electronic databases (PubMed, EMBASE, CINAHL, CENTRAL) were systematically searched from inception to 18 June 2020. Additional sources include searches of trial registrations, manual screening of reference lists and requests to experts. We included randomised controlled trials (RCTs) evaluating the effect of GAT on falls with at least 6-month follow-up among community-dwelling people aged 60+ years. Two reviewers independently screened studies against eligibility criteria, extracted relevant information and appraised studies for bias. Random-effects meta-analytic models were employed to pool effect estimates.
eleven studies with 1,131 participants were included. A meta-analysis in which an outlier study was excluded showed that GAT reduces fall rates by 42% (incidence rate ratio 0.58, 95% confidence interval [CI] 0.39-0.81, I2 = 0.00%; moderate certainty; seven RCTs). Moreover, proportion with fall-related fractures and proportion of fallers was reduced by 81% (risk ratio [RR] 0.19, 95% CI 0.06-0.56, I2 = 0.00%; very low certainty; two RCTs) and 43% (RR 0.57, 95% CI 0.4-to 0.8, I2 = 47.08%; low certainty; 11 RCTs), respectively.
our results show that GAT significantly reduces the number of falls and prevents fall-related fractures in older community dwellers. GAT is a promising and feasible exercise modality; however, studies of high quality should be conducted to support a robust conclusion.
PROSPERO; CRD42020191051.
老年人跌倒很常见,可能会产生灾难性后果。一种新型的特定任务的运动模式,步态适应性训练(GAT),已显示出有希望的预防作用。本系统评价和荟萃分析综合了关于 GAT 对社区居住的老年人跌倒和跌倒相关骨折的影响的证据。
从创建到 2020 年 6 月 18 日,系统地检索了电子数据库(PubMed、EMBASE、CINAHL、CENTRAL)。其他来源包括对试验注册的搜索、参考文献列表的手动筛选以及向专家的请求。我们纳入了随机对照试验(RCT),评估了 GAT 对社区居住的 60 岁以上人群至少 6 个月随访的跌倒效果。两名审查员独立筛选研究是否符合纳入标准,提取相关信息并评估研究偏倚。采用随机效应荟萃分析模型来汇总效应估计值。
纳入了 11 项研究,共 1131 名参与者。一项排除了异常值研究的荟萃分析表明,GAT 可使跌倒率降低 42%(发生率比 0.58,95%置信区间 [CI] 0.39-0.81,I2=0.00%;中等确定性;7 项 RCT)。此外,跌倒相关骨折的比例和跌倒者的比例分别降低了 81%(风险比 [RR] 0.19,95%CI 0.06-0.56,I2=0.00%;极低确定性;2 项 RCT)和 43%(RR 0.57,95%CI 0.4-0.8,I2=47.08%;低确定性;11 项 RCT)。
我们的结果表明,GAT 可显著减少社区老年人的跌倒次数并预防跌倒相关骨折。GAT 是一种有前途且可行的运动模式;然而,应开展高质量的研究来支持可靠的结论。
PROSPERO;CRD42020191051。