Department of Interventional Neurosurgery, Clinica Angloamericana, Peru.
Clinica Angloamericana, Peru.
Neuroradiol J. 2021 Aug;34(4):370-372. doi: 10.1177/19714009211024632. Epub 2021 Jun 13.
Retinoblastoma is the most frequent ocular malignancy in the pediatric population and intra-arterial chemotherapy has emerged as the first-line treatment of this entity with cure rates ranging from 33-100%, depending on the severity of the disease. We present the case of an advanced retinoblastoma in a pediatric patient who underwent intra-arterial chemotherapy through a contralateral route due to unsuccessful catheterization of the ophthalmic artery. The patient was diagnosed with a class D retinoblastoma which underwent the catheterization of the ophthalmic artery through the contralateral internal carotid and through the anterior communicating artery. In this case, intra-arterial chemotherapy administration was successfully delivered without complications. Contralateral routes for intra-arterial chemotherapy are safe and allow adequate penetration of the chemotherapeutic drugs in cases where a well-developed anterior communicating artery is present.
视网膜母细胞瘤是儿童中最常见的眼部恶性肿瘤，动脉内化疗已成为该疾病的一线治疗方法，治愈率为 33-100%，具体取决于疾病的严重程度。我们报告了一例儿科晚期视网膜母细胞瘤患者的病例，由于未能成功进行眼动脉插管，该患者通过对侧途径进行了动脉内化疗。该患者被诊断为 D 级视网膜母细胞瘤，通过对侧颈内动脉和前交通动脉进行了眼动脉插管。在这种情况下，动脉内化疗的给药成功进行，没有并发症。在存在发育良好的前交通动脉的情况下，对侧动脉内化疗途径是安全的，并允许化疗药物充分渗透。
