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拳击与感觉运动训练治疗帕金森病的随机双盲对照试验

Boxing vs Sensory Exercise for Parkinson's Disease: A Double-Blinded Randomized Controlled Trial.

机构信息

Movement Disorders Research and Rehabilitation Centre, Wilfrid Laurier University, Waterloo, ON, Canada.

出版信息

Neurorehabil Neural Repair. 2021 Sep;35(9):769-777. doi: 10.1177/15459683211023197. Epub 2021 Jun 13.


DOI:10.1177/15459683211023197
PMID:34121511
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8414806/
Abstract

. Exercise is increasingly becoming recognized as an important adjunct to medications in the clinical management of Parkinson's disease (PD). Boxing and sensory exercise have shown immediate benefits, but whether they continue beyond program completion is unknown. This study aimed to investigate the effects of boxing and sensory training on motor symptoms of PD, and whether these benefits remain upon completion of the intervention. . In this 20-week double-blinded randomized controlled trial, 40 participants with idiopathic PD were randomized into 2 treatment groups, (n = 20) boxing or (n = 20) sensory exercise. Participants completed 10 weeks of intervention. Motor symptoms were assessed at (week 0, 10, and 20) using the Unified Parkinson's Disease Rating Scale (UPDRS-III). Data were analyzed using SPSS, and repeated-measures ANOVA was conducted. . A significant interaction effect between groups and time were observed (1, 39) = 4.566, = .036, where the sensory group improved in comparison to the boxing group. Post hoc analysis revealed that in comparison to boxing, the effects of exercise did not wear off at washout (week 20) < .006. . Future rehabilitation research should incorporate similar measures to explore whether effects of exercise wear off post intervention.

摘要

运动在帕金森病(PD)的临床管理中越来越被认为是药物治疗的重要辅助手段。拳击和感觉运动训练已显示出即时的益处,但它们在完成计划后是否持续存在尚不清楚。本研究旨在调查拳击和感觉运动训练对 PD 运动症状的影响,以及这些益处是否在干预结束后仍然存在。

在这项为期 20 周的双盲随机对照试验中,40 名特发性 PD 患者被随机分为 2 个治疗组(n = 20),拳击组或感觉运动训练组。参与者完成了 10 周的干预。使用统一帕金森病评定量表(UPDRS-III)在(第 0、10 和 20 周)评估运动症状。使用 SPSS 进行数据分析,并进行重复测量方差分析。

观察到组间和时间的显著交互效应(1, 39)= 4.566, =.036,感觉运动组的改善优于拳击组。事后分析表明,与拳击相比,锻炼的效果在洗脱期(第 20 周)并未减弱(<.006)。

未来的康复研究应纳入类似措施,以探索干预后锻炼效果是否会减弱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1833/8414806/f31aee744564/10.1177_15459683211023197-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1833/8414806/7f4a8bd1370c/10.1177_15459683211023197-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1833/8414806/f31aee744564/10.1177_15459683211023197-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1833/8414806/7f4a8bd1370c/10.1177_15459683211023197-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1833/8414806/f31aee744564/10.1177_15459683211023197-fig2.jpg

相似文献

[1]
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[8]
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引用本文的文献

[1]
Feasibility of a Community-Based Boxing Program with Tailored Balance Training in Parkinson's Disease: A Preliminary Study.

Brain Sci. 2025-8-13

[2]
Effects of boxing interventions on physical fitness and health-related quality of life in older people with Parkinson's disease: a systematic review with meta-analysis.

Front Public Health. 2025-6-6

[3]
Intervention strategies for Parkinson's disease: the role of exercise and mitochondria.

Front Aging Neurosci. 2025-5-14

[4]
Effects of boxing exercise in people with Parkinson's disease: a systematic review.

Front Aging Neurosci. 2025-3-27

[5]
The Efficacy of Boxing Training on Patients with Parkinson's Disease: Systematic Review and Meta-Analysis.

Rev Neurol. 2024-12-20

[6]
Current interventional model for movement in Parkinson's disease: network meta-analysis based on the improvement of motor ability.

Front Aging Neurosci. 2024-9-10

[7]
Parkinson's disease motor intervention patterns: a network meta-analysis based on patient motor function.

Front Neurol. 2024-9-5

[8]
Effect of Boxing Exercises on the Functional Ability and Quality of Life of Individuals with Parkinson's Disease: A Systematic Review.

Eur J Investig Health Psychol Educ. 2024-5-7

[9]
Long-term impact of a community-based adapted boxing program on physical functioning and quality of life of individuals with Parkinson's disease.

NeuroRehabilitation. 2024

[10]
Exercise Made Accessible: the Merits of Community-Based Programs for Persons with Parkinson's Disease.

Curr Neurol Neurosci Rep. 2023-11

本文引用的文献

[1]
Counterpunching to improve the health of people with Parkinson's disease.

J Am Assoc Nurse Pract. 2021-4-7

[2]
Functional and Cognitive Improvement After an Intensive Inpatient Multidisciplinary Rehabilitation Program in Mild to Severe Parkinson's Disease: A Retrospective and Observational Study.

Front Neurol. 2021-3-18

[3]
Rehabilitation of Falls in Parkinson's Disease: Self-Perception vs. Objective Measures of Fall Risk.

Brain Sci. 2021-3-3

[4]
Gait Analysis of Old Individuals with Mild Parkinsonian Signs and Those Individuals' Gait Performance Benefits Little from Levodopa.

Risk Manag Healthc Policy. 2021-3-15

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Boxing with Parkinson's Disease: findings from a qualitative study using self-determination theory.

Disabil Rehabil. 2022-7

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A Mobile Phone App-Based Tai Chi Training in Parkinson's Disease: Protocol for a Randomized Controlled Study.

Front Neurol. 2021-1-13

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BMC Neurol. 2020-11-18

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The meaning of regular participation in vigorous-intensity exercise among men with Parkinson's disease.

Disabil Rehabil. 2022-6

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Effect of a High-Intensity Tandem Bicycle Exercise Program on Clinical Severity, Functional Magnetic Resonance Imaging, and Plasma Biomarkers in Parkinson's Disease.

Front Neurol. 2020-7-24

[10]
Analyzing the effects of PDSAFEx™ on the motor symptoms of Parkinson's disease: A retrospective study.

NeuroRehabilitation. 2020

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