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在尼日利亚伊巴丹对缺铁非妊娠患者进行的Ferastral临床试验。

Clinical trial of Ferastral in iron-deficient, non-pregnant patients in Ibadan, Nigeria.

作者信息

Esan G J, Oluboyede O A, Salako L A, Akande E O

出版信息

Scand J Haematol Suppl. 1977;32:322-25. doi: 10.1111/j.1600-0609.1977.tb01261.x.

Abstract

Fifteen patients with proven iron-deficiency anaemia treated with intramuscular injections of Ferastral, iron-poly (sorbitol-gluconic acid) complex, have been studied. Fourteen showed a satisfactory rise in haematocrit. No local or systemic complications were observed. One patient with iron-deficiency anaemia due to a bleeding malignant lesion did not achieve a satisfactory haematocrit level although the bone marrow showed iron repletion following the injection. It is concluded that Ferastral is an effective drug in the treatment of iron-deficiency anaemia.

摘要

对15例经证实为缺铁性贫血的患者进行了研究,他们接受了肌肉注射Ferastral(铁-聚山梨醇-葡萄糖酸复合物)治疗。14例患者的血细胞比容有令人满意的升高。未观察到局部或全身并发症。1例因恶性出血性病变导致缺铁性贫血的患者,尽管注射后骨髓显示铁储备充足,但血细胞比容水平未达到令人满意的程度。结论是Ferastral是治疗缺铁性贫血的有效药物。

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