Moawad Gaby N, Klebanoff Jordan S, Muldoon Olga, North Alexandra, Amdur Richard, Tyan Paul
Department of Obstetrics and Gynecology, Division of Minimally Invasive Gynecologic Surgery, The George Washington University Hospital, Washington, DC, United States.
Department of Obstetrics and Gynecology, Division of Minimally Invasive Gynecologic Surgery, The George Washington University Hospital, Washington, DC, United States.
J Gynecol Obstet Hum Reprod. 2021 Nov;50(9):102181. doi: 10.1016/j.jogoh.2021.102181. Epub 2021 Jun 12.
To determine whether perioperative narcotic utilization at the time of hysterectomy has decreased since 2012.
Retrospective cohort study.
Academic university hospital.
Patients who underwent a laparoscopic hysterectomy for benign indications between January 2012 and December 2018.
Perioperative narcotics administration.
We identified 651 patients who underwent a hysterectomy for benign indications from 2012 to 2018. Of these, 377 surgeries were performed using robotic-assistance (58%) and the remainder (42%) were performed by conventional laparoscopy. Narcotic utilization declined significantly by year for both intra-operative and post-operative periods (both p<.001). The largest decline for intraoperative morphine milligram equivalents (MME) was between 2016 and 2017, while for post-operative MME, it was between 2012 and 2013. The pattern remained significant after adjusting for covariates. Intraoperative MME administration was correlated with postoperative MME use (Spearman r = 0.23, p<.001). Of the demographic variables only Body Mass Index was significantly associated with perioperative narcotic administration.
Administration of opioids for intraoperative and postoperative pain after minimally invasive hysterectomy substantially decreased from 2012 to 2018. Intraoperative narcotic utilization was correlated with immediate postoperative narcotic consumption. Heightened awareness of opioid administration practices during and immediately following surgery is critically important to decreasing risk of chronic opioid dependence and providing the best possible care for the patients we serve.
确定自2012年以来子宫切除术中围手术期麻醉药物的使用量是否有所下降。
回顾性队列研究。
大学附属医院。
2012年1月至2018年12月期间因良性指征接受腹腔镜子宫切除术的患者。
围手术期麻醉药物给药。
我们确定了2012年至2018年期间因良性指征接受子宫切除术的651例患者。其中,377例手术采用机器人辅助(58%),其余(42%)采用传统腹腔镜手术。术中及术后麻醉药物的使用量逐年显著下降(均p<0.001)。术中吗啡毫克当量(MME)下降幅度最大的是2016年至2017年,而术后MME下降幅度最大的是2012年至2013年。在调整协变量后,该模式仍然显著。术中MME给药与术后MME使用相关(Spearman相关系数r = 0.23,p<0.001)。在人口统计学变量中,只有体重指数与围手术期麻醉药物给药显著相关。
2012年至2018年期间,微创子宫切除术后术中及术后疼痛的阿片类药物使用量大幅下降。术中麻醉药物的使用与术后即刻麻醉药物的消耗相关。提高手术期间及术后即刻阿片类药物给药实践的认识对于降低慢性阿片类药物依赖风险以及为我们所服务的患者提供尽可能最佳的护理至关重要。