Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Immunology and Allergy, The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
Iran J Allergy Asthma Immunol. 2021 Jun 6;20(3):263-270. doi: 10.18502/ijaai.v20i3.6342.
Allergic rhinitis (AR) is a prevalent disease affecting the quality of life of patients throughout the world. This study aimed to assess the prevalence of AR and its association with chronic rhinosinusitis (CRS) in the adult population living in Bushehr, southwestern part of Iran. In this population-based study, a total of 5420 individuals aged 15-65 years were selected through a multi-stage, cluster, random sampling method from which 5201 of them completed the Global Allergy and Asthma Network of Excellence (GA2LEN) questionnaire (Response rate=96.1%). The prevalence of AR, based on Allergic Rhinitis and Its Impact on Asthma (ARIA) classification (mild or moderate; intermittent or persistent) was calculated and the association of AR and CRS was evaluated using a multiple logistic regression model. The overall prevalence of AR was 28.8%, and for the intermittent and persistent AR were 25.9% (out of which 81.34% were moderate to severe) and 74.1% respectively. Moreover, the prevalence of AR was significantly higher in health workers and smokers (p=0.002 and p<0.001, respectively). Furthermore, an association was found between AR and CRS (p<0.001, aOR: 4.68, 95%CI: 4.07-5.39), and also, between the persistent AR and CRS as compared with the intermittent (p<0.001, aOR: 4.21, 95%CI: 3.40-5.22). The present study showed that the prevalence of AR in Bushehr (Southwestern part of Iran) was significantly high. In addition, the results indicated a strong association between AR and CRS, especially in individuals with moderate to severe persistent AR.
变应性鼻炎（AR）是一种普遍的疾病，影响着全世界患者的生活质量。本研究旨在评估伊朗西南部布什尔地区成年人群中 AR 的患病率及其与慢性鼻-鼻窦炎（CRS）的关系。在这项基于人群的研究中，采用多阶段、聚类、随机抽样方法，从 5420 名 15-65 岁的人群中选择了 5201 人完成了全球过敏和哮喘网络卓越中心（GA2LEN）问卷（应答率=96.1%）。根据变应性鼻炎及其对哮喘的影响（ARIA）分类（轻度或中度；间歇性或持续性）计算了 AR 的患病率，并使用多因素逻辑回归模型评估了 AR 与 CRS 的关系。AR 的总患病率为 28.8%，间歇性和持续性 AR 的患病率分别为 25.9%（其中 81.34%为中重度）和 74.1%。此外，卫生工作者和吸烟者的 AR 患病率明显较高（p=0.002 和 p<0.001）。此外，还发现 AR 与 CRS 之间存在关联（p<0.001，比值比[aOR]：4.68，95%置信区间[CI]：4.07-5.39），以及持续性 AR 与 CRS 之间的关联（与间歇性相比，p<0.001，aOR：4.21，95%CI：3.40-5.22）。本研究表明，布什尔（伊朗西南部）的 AR 患病率显著较高。此外，结果表明 AR 与 CRS 之间存在很强的关联，特别是在中重度持续性 AR 患者中。
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