Bhattacharyya Pooja, Bryan Andrew, Atluri Vidya, Ma Jimmy, Durowoju Lindsey, Bandhlish Anshu, Boonyaratanakornkit Jim
Vaccine and Infectious Disease Division, Fred Hutch Cancer Research Center, Seattle, WA, 98109, USA.
Division of Oncology, University of Washington, Seattle, WA, 98109, USA.
Leuk Res Rep. 2021 May 24;15:100254. doi: 10.1016/j.lrr.2021.100254. eCollection 2021.
MRSA enterocolitis is under-recognized in the setting of PCR testing. In this case report, we describe risk factors, the importance of stool culture, and the third published case of MRSA enterocolitis in a patient with leukemia. In addition, we performed a retrospective analysis of all stool cultures at our institution that have grown , and we describe an additional five cases. We also report the diagnostic yield of organisms detected by culture, but not on the FilmArray panel. While rare, these cases demonstrate that MRSA in stool may indicate a severe and potentially life-threatening infection, particularly in immunocompromised persons.
在聚合酶链反应（PCR）检测背景下，耐甲氧西林金黄色葡萄球菌（MRSA）肠炎未得到充分认识。在本病例报告中，我们描述了风险因素、粪便培养的重要性以及白血病患者中第三例已发表的MRSA肠炎病例。此外，我们对本机构所有培养出[具体细菌名称未给出]的粪便培养物进行了回顾性分析，并描述了另外五例病例。我们还报告了通过培养检测到但FilmArray检测板未检测到的微生物的诊断率。虽然罕见，但这些病例表明粪便中的MRSA可能预示着严重且可能危及生命的感染，尤其是在免疫功能低下的人群中。
