Cardiology Department, Royal Victoria Hospital, Belfast, United Kingdom.
Curr Cardiol Rev. 2022;18(1):e170621194128. doi: 10.2174/1573403X17666210617094735.
The 'gold standard' in the management of left main coronary artery disease has historically been coronary artery bypass surgery. Recent innovations in drug-eluting stent technology coupled with the increasing utility of physiology and imaging guidance for procedures have led to an evolving role of percutaneous coronary intervention in left main disease of low and intermediate anatomical complexity. This revascularization modality carries the clear advantage of being less invasive and significantly reduced recovery times. This practice is currently supported by international guidelines, however, it remains a controversial topic in the field of interventional cardiology, and the long-term outcomes of a percutaneous strategy have been questioned. This review describes the current evidence base for the assessment and choice of intervention in left main coronary artery disease. The percutaneous revascularization techniques and use of imaging to optimize procedures and improve clinical outcomes have been discussed.
左主干冠状动脉疾病的传统治疗“金标准”一直是冠状动脉旁路移植术。药物洗脱支架技术的最新创新,以及生理和影像学指导程序的应用日益广泛,使得经皮冠状动脉介入治疗在解剖结构简单和中等复杂的左主干疾病中的作用不断演变。这种血运重建方式具有明显的优势,即创伤更小,恢复期大大缩短。目前,这一治疗方法得到了国际指南的支持,然而,它在介入心脏病学领域仍是一个有争议的话题,经皮治疗策略的长期结果一直受到质疑。本综述描述了左主干冠状动脉疾病评估和介入选择的当前证据基础。讨论了经皮血运重建技术和影像学的应用,以优化手术过程,改善临床结果。