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[我们单剂量庆大霉素治疗泌尿系统感染的经验]

[Our experience of treating urological infections with a single dose of gentamycin].

作者信息

Belovezhdov N, Angelova I, Stefanov G, Stoianova M, Chakŭrski I

出版信息

Vutr Boles. 1988;27(2):101-3.

PMID:3414092
Abstract

31 patients with a urological infection caused by a bacterial strain susceptible to gentamycin were treated by a single injection of 240 mg of gentamycin. 11 patients (35.5%) fully recovered, the infection was eliminated and the clinical symptoms and signs disappeared. Better results were achieved in patients with infection of the lower urinary tract without pyelonephritis, 7 out of 15 patients (46%) recovered. Out of 16 patients with pyelonephritis only 4 were cured (25%). Of 10 patients with nephrolithiasis only 1 was cured, in the remaining 9 patients the treatment was without effect. In the group of patients who recovered the patients with E. coli infection prevailed while in the group of unsuccessfully treated patients other bacteria prevailed. No side effects were found. The conclusion is that the treatment with a single gentamycin dose could be applied successfully in patients with an infection of the lower urinary tract without pyelonephritis, morphologic changes in the urinary system or nephrolithiasis.

摘要

31例由对庆大霉素敏感的菌株引起的泌尿系统感染患者接受了单次注射240毫克庆大霉素的治疗。11例患者(35.5%)完全康复,感染消除,临床症状和体征消失。下尿路感染且无肾盂肾炎的患者治疗效果更好,15例患者中有7例(46%)康复。16例肾盂肾炎患者中仅4例治愈(25%)。10例肾结石患者中仅1例治愈,其余9例患者治疗无效。在康复的患者组中,大肠杆菌感染的患者占多数,而在治疗未成功的患者组中,其他细菌占多数。未发现副作用。结论是,单次剂量的庆大霉素治疗可成功应用于下尿路感染且无肾盂肾炎、泌尿系统形态学改变或肾结石的患者。

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