Bosselmann H P, Gaede B, Franke A, Lachhein L
Nephrologischen Abteilung, Medizinischen Akademie Magdeburg.
Z Gesamte Inn Med. 1988 May 15;43(10):271-3.
It is reported on the treatment of three patients with a hyperviscosity syndrome in IgG-plasmocytoma. Before every polychemotherapy cycle a plasma exchange was carried out, when the total protein in the serum and the immunoglobulins were essentially increased and clinical symptoms of the hyperviscosity syndrome were existing. The results and the possible effects on the efficacy of the therapy with cytostatic agents are discussed. In the light of our experiences we can recommend the membrane plasma filtration treatment as symptomatic therapeutic measure in the hyperviscosity syndrome.
本文报道了3例IgG型浆细胞瘤伴高黏滞综合征患者的治疗情况。在每个多药化疗周期前，当血清总蛋白和免疫球蛋白显著升高且存在高黏滞综合征的临床症状时，进行血浆置换。文中讨论了该治疗结果以及对细胞毒性药物治疗效果可能产生的影响。根据我们的经验，我们推荐膜式血浆滤过治疗作为高黏滞综合征的对症治疗措施。
