Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China.
Graefes Arch Clin Exp Ophthalmol. 2021 Nov;259(11):3461-3468. doi: 10.1007/s00417-021-05240-x. Epub 2021 Jun 18.
To evaluate the effect of inferior oblique muscle belly transposition (IOBT) on vertical deviation (VD) in primary position and inferior oblique overaction (IOOA).
Twenty-eight patients who underwent unilateral IOBT for mild hypertropia (≤ 10) due to unilateral IOOA were included. Surgical results regarding the correction of hypertropia, IOOA, and fovea disc angle (FDA) were analyzed and compared between groups A (VD ≤ 5) and B (5 < VD ≤ 10).
IOBT showed an overall reduction of 5.86 (± 2.24) of primary position VD, a mean correction of 1.00 (± 0.27) of IOOA, and an average change of 1.83° (± 3.02°) of FDA. The surgical success rate of IOBT for VD correction and IOOA elimination in all patients was 68% and 71%, respectively. The correction of VD was correlated with preoperative VD significantly (r = 0.86, p < 0.001). Consistently, IOBT demonstrated comparable efficacy in reduction of VD between group A and group B (p = 0.507). Furthermore, the two groups were comparable in the success rates for correcting VD and IOOA (both p > 0.05). None of the patients developed consecutive hypotropia, postoperative contralateral IOOA, or anti-elevation syndrome postoperatively.
IOBT achieved satisfactory outcomes in patients with mild primary position VD (≤ 10) that is associated with unilateral IOOA, without any risk of overcorrection of VD and contralateral IOOA for a follow-up period of up to 12 months. This procedure is considered effective and safe alternative for weakening the IO in patients with appropriate surgical indications.
评估下斜肌腹移位术(IOBT)对原发性垂直斜视(VD)和下斜肌亢进(IOOA)的影响。
共纳入 28 例因单侧 IOOA 导致轻度(≤10)上斜视的患者行单侧 IOBT。分析并比较 A 组(VD≤5)和 B 组(5<VD≤10)中手术矫正上斜视、IOOA 和黄斑碟角(FDA)的结果。
IOBT 使原发性位置 VD 平均减少 5.86(±2.24),IOOA 平均矫正 1.00(±0.27),FDA 平均变化 1.83°(±3.02°)。IOBT 治疗所有患者的 VD 矫正和 IOOA 消除的手术成功率分别为 68%和 71%。VD 矫正与术前 VD 显著相关(r=0.86,p<0.001)。同样,IOBT 在 A 组和 B 组之间在降低 VD 方面具有相当的疗效(p=0.507)。此外,两组在矫正 VD 和 IOOA 的成功率方面相似(均 p>0.05)。所有患者均未出现连续下斜视、术后对侧 IOOA 或术后抗抬高综合征。
对于伴有单侧 IOOA 的轻度原发性 VD(≤10)患者,IOBT 可获得满意的结果,在长达 12 个月的随访期间,没有 VD 和对侧 IOOA 过矫正的风险。对于有适当手术适应证的患者,该手术被认为是削弱 IO 的有效且安全的替代方法。