质子泵抑制剂直接阻断人醚-去极化激活的钾离子通道（hERG），并独立增加一大群美国退伍军人QTc间期延长的风险。
Proton Pump Inhibitors Directly Block hERG-Potassium Channel and Independently Increase the Risk of QTc Prolongation in a Large Cohort of US Veterans.
作者信息
Lazzerini Pietro Enea, Cartocci Alessandra, Qu Yongxia Sarah, Saponara Simona, Furini Simone, Fusi Fabio, Fabris Frank, Gamberucci Alessandra, El-Sherif Nabil, Cevenini Gabriele, Pettini Francesco, Laghi-Pasini Franco, Acampa Maurizio, Bertolozzi Iacopo, Capecchi Pier Leopoldo, Lazaro Deana, Boutjdir Mohamed
机构信息
Department of Medical Sciences, Surgery and Neurosciences (P.E.L., F.L.-P., P.L.C.), University of Siena, Italy.
Department of Medical Biotechnologies (A.C., S.F., G.C., F.P.), University of Siena, Italy.
出版信息
Circ Arrhythm Electrophysiol. 2021 Jul;14(7):e010042. doi: 10.1161/CIRCEP.121.010042. Epub 2021 Jun 18.
PMID:34143643
Abstract
[Figure: see text].
摘要
[图：见正文]。
Zotero 插件