Bougle D, Bureau F, Foucault P, Duhamel J F, Muller G, Drosdowsky M
Service de Néonatologie, Centre Hospitalier Universitaire, Caen, France.
Am J Clin Nutr. 1988 Sep;48(3):652-4. doi: 10.1093/ajcn/48.3.652.
To assess the molybdenum supply and requirements of preterm infants, Mo concentration was determined in milk from mothers of 6 term and 11 preterm newborns; no difference was found between fore- and hindmilk and no diurnal variations were found during 24-h collections. Respective values (means +/- SD) of term and preterm milks were 10.2 +/- 3.7 and 4.0 +/- 3.7 micrograms/L (106.2 +/- 38.5 and 41.7 +/- 38.5 nmol/L) at 3-5 d of lactation, 4.8 +/- 3.9 and 3.7 +/- 3.8 micrograms/L (50.0 +/- 4.6 and 38.5 +/- 39.6 nmol/L) at 7-10 d, 1.5 +/- 1.4 and 1.4 +/- 0.9 micrograms/L (15.6 +/- 14.6 and 14.6 +/- 9.6 nmol/L) at 14 d, 2.6 +/- 2.2 and 1.9 +/- 1.4 micrograms/L (27.1 +/- 22.9 and 19.8 +/- 14.6 nmol/L) at 1 mo, and 0.2 and 1.2 +/- 0.5 micrograms/L (2.1 and 12.5 +/- 5.2 nmol/L) at 2 mo. A statistical difference was found between term and preterm milk at 3-5 d of lactation. During lactation significant changes were found between the periods 3-5 d and 7-10 d, 14 d, 1 mo (p less than 0.01) and 2 mo (p less than 0.05) of lactation and between 7-10 d and 14 d (p less than 0.05). According to the requirements of the preterm infant, a supplementation of 2-3 micrograms.kg-1.d-1 by enteral route is suggested.
为评估早产儿的钼供应和需求情况，测定了6名足月儿和11名早产儿母亲乳汁中的钼浓度；未发现前奶和后奶之间存在差异，且在24小时的采集过程中未发现日变化。足月母乳和早产母乳在产后3 - 5天的各自值（均值±标准差）分别为10.2±3.7和4.0±3.7微克/升（106.2±38.5和41.7±38.5纳摩尔/升），产后7 - 10天分别为4.8±3.9和3.7±3.8微克/升（50.0±4.6和38.5±39.6纳摩尔/升），产后14天分别为1.5±1.4和1.4±0.9微克/升（15.6±14.6和14.6±9.6纳摩尔/升），产后1个月分别为2.6±2.2和1.9±1.4微克/升（27.1±22.9和19.8±14.6纳摩尔/升），产后2个月分别为0.2和1.2±0.5微克/升（2.1和12.5±5.2纳摩尔/升）。在产后3 - 5天，足月母乳和早产母乳之间存在统计学差异。在哺乳期，产后3 - 5天与7 - 10天、14天、1个月（p<0.01）和2个月（p<0.05）以及7 - 10天与14天（p<0.05）之间均发现有显著变化。根据早产儿的需求，建议经肠道途径补充2 - 3微克·千克⁻¹·天⁻¹。
