Gómez-Álzate Alejandra María, Hidalgo-López Catalina, García-Valencia Jenny, Martínez-Zamora Marta, Aguirre-Acevedo Daniel Camilo, Cuartas-Arias Mauricio, Arcos-Burgos Mauricio, Valencia-Evhecerry Johanna, Lopez-Jaramillo Carlos, Palacio-Ortiz Juan David
Departamento de Psiquiatría, Facultad de Medicina, Universidad de Antioquia. Hospital Universitario San Vicente de Paúl, Medellín, Colombia; Grupo de investigación en psiquiatría (GIPSI), Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Departamento de Psiquiatría, Facultad de Medicina, Universidad de Antioquia. Hospital Universitario San Vicente de Paúl, Medellín, Colombia; Instituto de Investigaciones Médicas, Universidad de Antioquia, Medellín, Colombia.
Rev Colomb Psiquiatr (Engl Ed). 2021 Jun 16. doi: 10.1016/j.rcp.2021.03.007.
We aim to determine the prevalence of mental disorders in siblings of children with attention deficit hyperactivity disorder (ADHD), and to determine how psychosocial adversity factors relate to this psychopathology, in a low-middle income country (Colombia).
We evaluated subjects with ADHD diagnosed according to the DSM-5 criteria, one of their parents and one of their siblings (ages 8-19). We used the ADHD rating scale and a set of instruments to assess the presence of mental disorders as well as psychosocial adversity.
We evaluated 74 trios formed by the index case with ADHD, one sibling and one of the parents. We found that 24.3% of the participating siblings also met the criteria for ADHD and another 24.3% for other psychiatric disorders. The risk of these siblings having ADHD increased further when one of the parents reported a history of ADHD. We also found that 28.3% of the families faced high levels of psychosocial adversity as per their scores in the Rutter Adversity Index.
Siblings of subjects with ADHD showed a significant risk for ADHD and other mental disorders. That risk increased if a parent reported a history of ADHD and also when two or more psychosocial adversity factors were present. This study supports the importance of early detection in efforts to decrease the risk for other siblings.
我们旨在确定在一个中低收入国家（哥伦比亚），注意缺陷多动障碍（ADHD）患儿的兄弟姐妹中精神障碍的患病率，并确定社会心理逆境因素与这种精神病理学之间的关系。
我们评估了根据《精神疾病诊断与统计手册》第五版（DSM-5）标准诊断为ADHD的受试者、他们的一位父母和一位兄弟姐妹（年龄在8至19岁之间）。我们使用ADHD评定量表和一组工具来评估精神障碍的存在以及社会心理逆境。
我们评估了由ADHD索引病例、一位兄弟姐妹和一位父母组成的74个三人组。我们发现，24.3%的参与研究的兄弟姐妹也符合ADHD标准，另有24.3%符合其他精神障碍标准。当父母一方报告有ADHD病史时，这些兄弟姐妹患ADHD的风险进一步增加。我们还发现，根据拉特逆境指数得分，28.3%的家庭面临高水平的社会心理逆境。
ADHD受试者的兄弟姐妹显示出患ADHD和其他精神障碍的显著风险。如果父母报告有ADHD病史，以及当存在两个或更多社会心理逆境因素时，这种风险会增加。这项研究支持了早期发现对于降低其他兄弟姐妹风险的重要性。
