Wang Ji, Jiang Lin, Ma Xuejin, Li Tingchao, Liu Heng, Chen Xiaoxi, Li Shiguang
Department of Radiology, The First People's Hospital of Zunyi, The Third Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Department of Pathology, The First People's Hospital of Zunyi, The Third Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Front Oncol. 2021 Jun 4;11:685070. doi: 10.3389/fonc.2021.685070. eCollection 2021.
Solitary plasmacytoma (SP) is a malignant tumor caused by the monoclonal proliferation of plasma cells, representing less than 5% of plasma cell tumors. SP can be categorized into two groups: solitary bone plasmacytoma (SBP) and solitary extramedullary plasmacytoma (SEP). SEP most commonly occurs in the head and neck and is rarely located in the reproductive system. Here, we report a case of a 77-year-old woman with SEP in the cervix who had a 7-day history of vaginal bleeding. Ultrasonography and magnetic resonance imaging (MRI) showed an oval mass in the cervix, which was initially considered as neoplastic lesions and highly suspected to be cervical cancer, but cervical leiomyoma and other benign tumors cannot be completely excluded. Subsequently, cervical biopsy showed that the tumor was SEP, and then the patient underwent surgery. The postoperative pathological diagnosis was also SEP, which confirmed the radiologist's misjudgment. In conclusion, SEP that occurs in the cervix is remarkably rare, and only nine cases have been reported in the cervix. No case reports to date have described in detail the imaging findings of cervical SEP. This study demonstrates the MRI imaging characteristics of a patient with SEP of the cervix and reviews the imaging findings of SEP reported in the previous literature, in order to provide more extensive insights for radiologists to consider the differential diagnosis of cervical lesions.
孤立性浆细胞瘤（SP）是一种由浆细胞单克隆增殖引起的恶性肿瘤，占浆细胞肿瘤的比例不到5%。SP可分为两组：孤立性骨浆细胞瘤（SBP）和孤立性髓外浆细胞瘤（SEP）。SEP最常发生于头颈部，很少位于生殖系统。在此，我们报告一例77岁女性，患有宫颈SEP，有7天阴道出血史。超声检查和磁共振成像（MRI）显示宫颈有一个椭圆形肿块，最初被认为是肿瘤性病变，高度怀疑为宫颈癌，但不能完全排除宫颈平滑肌瘤和其他良性肿瘤。随后，宫颈活检显示肿瘤为SEP，然后患者接受了手术。术后病理诊断也为SEP，证实了放射科医生的误诊。总之，发生在宫颈的SEP非常罕见，宫颈仅报道过9例。迄今为止，尚无病例报告详细描述宫颈SEP的影像学表现。本研究展示了一名宫颈SEP患者的MRI成像特征，并回顾了既往文献中报道的SEP的影像学表现，以便为放射科医生考虑宫颈病变的鉴别诊断提供更广泛的见解。
