Bactec需氧树脂培养基与高渗血液培养基的比较。

A comparison between Bactec aerobic resin and hypertonic blood culture media.

作者信息

Sjöberg L, Fredlund H, Duberg A S

机构信息

Department of Clinical Microbiology, Orebro Medical Center Hospital, Sweden.

出版信息

APMIS. 1988 Aug;96(8):720-2. doi: 10.1111/j.1699-0463.1988.tb00935.x.

DOI:10.1111/j.1699-0463.1988.tb00935.x

PMID:3415846

Abstract

The presence of antimicrobial agents in patients' blood is thought to represent an important source of false-negative blood cultures. This has led to the incorporation of agents with inhibitory effects on antimicrobial drugs into culture medium. In the present study, Bactec aerobic resin-containing blood culture medium was compared with Bactec hypertonic blood culture medium. 504 patients receiving cytostatic and/or antibiotic treatment were studied. Sensitivity calculations on detection of bacteremia in these patients gave 0.91 for the resin medium and 0.79 for the hypertonic blood culture system and showed a significant difference (p = 0.016). In addition, the resin-containing system more rapidly detected positive cultures than the hypertonic system.

摘要

患者血液中抗菌药物的存在被认为是血培养假阴性的一个重要来源。这导致了将对抗菌药物有抑制作用的试剂加入到培养基中。在本研究中，对含Bactec需氧树脂的血培养基和Bactec高渗血培养基进行了比较。研究了504例接受细胞抑制剂和/或抗生素治疗的患者。对这些患者菌血症检测的敏感性计算结果显示，树脂培养基为0.91，高渗血培养系统为0.79，两者存在显著差异（p = 0.016）。此外，含树脂系统比高渗系统能更快速地检测出阳性培养物。