Hidru Hagos Degefa, Gebremedhine Haftay, Gebretsadik Alem, Teame Hirut, Negash Hadush, Mengesha Meresa Berwo
College of Medicine and Health Sciences, Department of Public Health, Adigrat University, Adigrat, Ethiopia.
College of Medicine and Health Sciences, Department of Laboratory Unit of Medical Microbiology, Adigrat University, Adigrat, Ethiopia.
Int J Food Sci. 2021 Jun 1;2021:7816872. doi: 10.1155/2021/7816872. eCollection 2021.
Food insecurity is the shortage of both the quantity and quality of food and a negative impact on the overall nutritional and health status of people with human immunodeficiency virus (HIV). Ethiopia is intensely affected by food insecurity which is about 87.4% of adult people living with human immuno deficiency virus (HIV) are still facing shortage to have access to safe, sufficient, and nutritious food for themselves and their family. However, there is no concrete scientific evidence established at the national level in Ethiopia. Hence, this review gave special emphasis on adult people with human immunodeficiency virus (HIV) to estimate the pooled prevalence of food insecurity and its associated factor at the national level in Ethiopia.
Studies were retrieved from selected electronic data bases, including PubMed/Medlin, Cochrane library, Sciences Direct, Google, and Google Scholar. Random-effects model meta-analysis was used to estimate the pooled prevalence of food insecurity and its associated factors at 95% confidence interval with odds ratio (OR) using statistical -software version 3.6.1. Moreover, quality appraisal of the included studies, publication bias was checked using the funnel symmetry test, and heterogeneity was checked using forest plot and inverse variance square ( ). The searches were restricted to articles published in the English language only, and Medical Subject Headings (MeSH terms) was used to help expand the search in advanced PubMed search.
A total of 650 articles were identified through the initial search of which 20 studies were included in the final review yielding a total sample size of 7,797 adult people with human immunodeficiency virus (HIV). The pooled prevalence of food insecurity was 52% (95% CI, 40%, 63%). Cluster of differentiation 4 (CD4) count < 350 cell/mm [AOR = 1.29 (95% CI, 1.08, 1.54)], develop opportunistic infection [AOR = 4.09 (95% CI, 2.47, 6.78)], rural residence [AOR = 1.59 (95% CI, 1.09, 2.34)], and World Health Organization (WHO) clinical stages III and IV [AOR = 1.98 (95% CI, 1.23, 3.19)] was among the significantly associated factors.
In this review, there was a high prevalence of food insecurity among adult people with human immunodeficiency virus. Therefore, the responsible stockholders should strengthen the system and procedure for early diagnosis of opportunistic infection, under nutrition, screening of underlying problems.
粮食不安全是指食物在数量和质量上的短缺,并且会对感染人类免疫缺陷病毒(HIV)人群的整体营养和健康状况产生负面影响。埃塞俄比亚深受粮食不安全问题的影响,约87.4%的成年HIV感染者仍面临着自身及家庭难以获取安全、充足且营养丰富食物的困境。然而,埃塞俄比亚在国家层面上尚未有具体的科学证据。因此,本综述特别关注成年HIV感染者,以估计埃塞俄比亚全国层面粮食不安全的合并患病率及其相关因素。
从选定的电子数据库中检索研究,包括PubMed/Medline、Cochrane图书馆、科学Direct、谷歌和谷歌学术。采用随机效应模型荟萃分析,使用统计软件版本3.6.1在95%置信区间下以优势比(OR)估计粮食不安全及其相关因素的合并患病率。此外,对纳入研究进行质量评估,使用漏斗对称检验检查发表偏倚,并使用森林图和逆方差平方检查异质性。检索仅限于仅以英文发表的文章,并使用医学主题词(MeSH词)来帮助在高级PubMed搜索中扩大检索范围。
通过初步检索共识别出650篇文章,其中20项研究纳入最终综述,产生了总计7797名成年HIV感染者的样本量。粮食不安全的合并患病率为52%(95%CI,40%,63%)。分化簇4(CD4)计数<350个细胞/mm[AOR = 1.29(95%CI,1.08,1.54)]、发生机会性感染[AOR = 4.09(95%CI,2.47,6.78)]、农村居住[AOR = 1.59(95%CI,1.09,2.34)]以及世界卫生组织(WHO)临床分期III和IV[AOR = 1.98(95%CI,1.23,3.19)]是显著相关因素。
在本综述中,成年HIV感染者中粮食不安全的患病率很高。因此,相关责任方应加强机会性感染的早期诊断、营养不足以及潜在问题筛查的系统和程序。