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子宫颈血行转移硬化性上皮样纤维肉瘤的首次描述。

First description of hematogenously metastasized sclerosing epithelioid fibrosarcoma arising in the uterine cervix.

作者信息

Eich Marie-Lisa, Morgenstern Bernd, Puesken Michael, Pappesch Roberto, Quaas Alexander, Schoemig-Markiefka Birgid

机构信息

Institute for Pathology, University Hospital Cologne, Cologne, Germany.

Department of Obstetrics and Gynecology, Medical Faculty, University Hospital Cologne, Cologne, Germany.

出版信息

Gynecol Oncol Rep. 2021 Jun 5;37:100801. doi: 10.1016/j.gore.2021.100801. eCollection 2021 Aug.

DOI:10.1016/j.gore.2021.100801
PMID:34159243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8193370/
Abstract

•First Case of hematogenously metastasized sclerosing epithelioid fibrosarcoma arising primarily in the cervix uteri.•Tumor cells were strongly and diffusely positive for MUC4.•Tumor showed a rare EWSR1-CREB3L2 gene fusion.

摘要

•首例主要起源于子宫颈的血行转移硬化性上皮样纤维肉瘤。

•肿瘤细胞MUC4呈强弥漫性阳性。

•肿瘤显示罕见的EWSR1-CREB3L2基因融合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0146/8193370/b1a48d20f9fe/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0146/8193370/7891c4b03dc5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0146/8193370/897921d0a185/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0146/8193370/b1a48d20f9fe/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0146/8193370/7891c4b03dc5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0146/8193370/897921d0a185/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0146/8193370/b1a48d20f9fe/gr3.jpg

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本文引用的文献

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Am J Surg Pathol. 2021 Mar 1;45(3):317-328. doi: 10.1097/PAS.0000000000001559.
2
Hybrid Low-Grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma of the Pancreas.胰腺混合性低级别纤维黏液样肉瘤和硬化性上皮样纤维肉瘤
J Gastrointest Cancer. 2020 Sep;51(3):1025-1029. doi: 10.1007/s12029-020-00369-0.
3
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Genes Chromosomes Cancer. 2020 Apr;59(4):217-224. doi: 10.1002/gcc.22822. Epub 2019 Nov 15.
4
Benign-looking primary fibrosarcoma of the uterus.外观良性的子宫原发性纤维肉瘤。
Pol J Pathol. 2019;70(2):148-152. doi: 10.5114/pjp.2019.87108.
5
Clinical Characteristics and efficacy of chemotherapy in sclerosing epithelioid fibrosarcoma.硬化性上皮样纤维肉瘤的临床特征和化疗疗效。
Med Oncol. 2018 Sep 5;35(11):138. doi: 10.1007/s12032-018-1192-6.
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