Szilágyi T, Deseö G
Acta Microbiol Acad Sci Hung. 1977;24(2):149-55.
Distribution and elimination of 32P-labelled endotoxin were studied in normal frogs and in frogs pretreated with a high dose of unlabelled endotoxin 24 hr previously. Like in other animals, the spleen and the liver of the frogs were found the most active R.E.S. organs. The alimentary tract too exhibited considerable R.E.S. activity. Pretreatment with unlabelled endotoxin resulted in a decrease of 32P-endotoxin uptake by the liver, the spleen and the alimentary tract. Evidence was obtained that the well-known effects of endotoxin on the R.E.S. of the mammals can be demonstrated in the frog as well.
研究了32P标记的内毒素在正常青蛙以及24小时前用高剂量未标记内毒素预处理的青蛙体内的分布和消除情况。与其他动物一样，青蛙的脾脏和肝脏是最活跃的网状内皮系统（R.E.S.）器官。消化道也表现出相当程度的网状内皮系统活性。用未标记内毒素预处理导致肝脏、脾脏和消化道对32P-内毒素的摄取减少。有证据表明，内毒素对哺乳动物网状内皮系统的众所周知的作用在青蛙中也可以得到证实。
