University Cardiology Clinic, Vascular Centre, Faculty of Medicine, Skopje, R.N. Macedonia.
Department of Internal Medicine and Emergency Room, Ospedale Buon Consiglio Fatebenefratelli, Naples, Italy.
Angiol Sosud Khir. 2021;27(2):62-72. doi: 10.33529/ANGIO2021108.
Many works aimed to determine factors that influence the onset of postthrombotic syndrome after an acute episode of deep venous thrombosis. We aimed to compare the prognostic value of the most proximal extent of thrombus (proximal and distal DVT) versus the residual thrombosis as identified by venous ultrasonography performed during follow-up.
We conducted a retrospective study of prospectively collected 1183 consecutive cohort patients in the RIETE registry after a first episode of deep venous thrombosis and assessed for postthrombotic syndrome after 12 months.
Multivariate analysis revealed that: residual thrombosis (OR 1.40; 95% CI 0,88-2,21), the presence of cancer (OR 1.38; 95% CI: 0,64-2,97), immobility (OR 1.31; 95% CI 0,70-2,43) and estrogen-containing drugs use (OR 2.08, 95% CI 0,63-6,83), all had a predictive value for the occurrence of PTS.
Our study results revealed that ultrasound finding of residual thrombosis is more predictive than proximal location of thrombus for postthrombotic syndrome after episode of deep venous thrombosis. Real life data from a large group of patients from the RIETE registry substantiates that.
许多研究旨在确定影响深静脉血栓形成急性发作后血栓后综合征发生的因素。我们旨在比较血栓最近端范围（近端和远端 DVT）与静脉超声在随访期间识别的残留血栓的预后价值。
我们对 RIETE 登记处前瞻性收集的 1183 例连续队列患者首次深静脉血栓形成后的情况进行了回顾性研究，并在 12 个月后评估了血栓后综合征的发生情况。
多变量分析显示：残留血栓（OR 1.40；95%CI 0.88-2.21）、癌症（OR 1.38；95%CI：0.64-2.97）、活动受限（OR 1.31；95%CI 0.70-2.43）和雌激素类药物使用（OR 2.08，95%CI 0.63-6.83）均对 PTS 的发生具有预测价值。
我们的研究结果表明，超声发现残留血栓比深静脉血栓形成后血栓后综合征的近端位置更具预测性。来自 RIETE 登记处的大量患者的真实数据证实了这一点。
