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溃疡性结肠炎行回肠可控性造口术的长期疗效和生活质量:系统评价。

Long-term outcome and quality of life after continent ileostomy for ulcerative colitis: A systematic review.

机构信息

St Mark's Hospital and Academic Institute, Harrow, UK.

Department of Surgery and Cancer, Imperial College London, London, UK.

出版信息

Colorectal Dis. 2021 Sep;23(9):2286-2299. doi: 10.1111/codi.15788. Epub 2021 Jul 18.

Abstract

AIM

The continent ileostomy allows evacuation of an ileal reservoir at a time convenient to the patient. It is a surgical option for patients with ulcerative colitis (UC) when a restorative option is not suitable or has not succeeded and the patient does not want a conventional end ileostomy. Continent ileostomy types include the Kock pouch, Barnett continent intestinal reservoir and T-pouch. All of the published evidence on the long-term outcome and quality of life after continent ileostomy for UC was systematically reviewed.

METHODS

A systematic review was performed in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies published between 1990 and 2020 were included. A descriptive synthesis was used due to the clinical heterogeneity.

RESULTS

The search returned 1655 abstracts and after screening of abstracts and full text review, 19 were included in the final review, involving 1602 patients. Operative mortality is low (0%-3.6%) after all types of continent ileostomy but reoperation rates are high (20.8%-65%) because of valve mechanism failures. Rates of fistulae (0%-25.5%) and stomal stenosis (0%-25%) can be relatively high postoperatively. Quality of life scores improve for most patients undergoing continent ileostomy, especially for patients converted from ileal pouch anal anastomosis. Overall, continent ileostomy retention is high in the long-term.

DISCUSSION

In the long-term, patients report high satisfaction and a good quality of life with continent ileostomy, despite high reoperation rates and complications. Newer technologies may reinvigorate interest in the continent ileostomy for this population.

摘要

目的

回肠贮袋造口术可让患者在方便的时候排空回肠贮袋。对于溃疡性结肠炎(UC)患者,如果不适合或未能成功进行修复性手术,且患者不想进行传统的末端回肠造口术,那么回肠贮袋造口术是一种手术选择。回肠贮袋造口术类型包括 Koch 袋、Barnett 回肠贮袋和 T 袋。本文系统回顾了所有关于 UC 患者行回肠贮袋造口术的长期结局和生活质量的相关证据。

方法

按照系统评价和荟萃分析的首选报告项目(PRISMA)指南进行系统评价。纳入了 1990 年至 2020 年期间发表的研究。由于临床异质性,采用描述性综合方法。

结果

检索到 1655 篇摘要,经过摘要和全文筛选后,最终有 19 项研究纳入了最终的综述,涉及 1602 名患者。所有类型的回肠贮袋造口术的手术死亡率均较低(0%-3.6%),但由于瓣膜机制失效,再次手术率较高(20.8%-65%)。术后瘘管(0%-25.5%)和造口狭窄(0%-25%)的发生率可能相对较高。大多数行回肠贮袋造口术的患者生活质量评分有所改善,尤其是从回肠袋肛管吻合术转为回肠贮袋造口术的患者。总的来说,回肠贮袋造口术在长期保留率较高。

讨论

从长期来看,尽管再次手术率和并发症较高,但患者对回肠贮袋造口术的满意度和生活质量仍较高。新技术可能会重新激发人们对这类人群行回肠贮袋造口术的兴趣。

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