Wu X L, Hu Y H, Gao S Z, Sun D, Liu L, Gu X Z
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1988 Jan;10(1):32-3.
From July 1958 to December 1979, 22 patients with retinoblastoma were treated postoperatively by radiotherapy. All were proved by pathology. There were 12 stage I, 1 stage II, 8 stage III and 1 stage IV lesions. Radiation dose was more than 15 Gy and most of the patients received 40-50 Gy in 4-5 weeks. The overall cancer free 5 year survival rate was 55% (12/22). The 5 year survival rate of stage I patients was 75% (9/12), and that of stage III patients was 38% (3/8). None of the stage II and IV patients survived. Dose of 40-50 Gy/4-5 wk is considered to be optimal for control of the tumor. Dose higher than 60 Gy/6 wk could lead to retarded growth in the orbital and temporal bony structures if the patient survives for ten years or more.
1958年7月至1979年12月，22例视网膜母细胞瘤患者术后接受放射治疗。所有病例均经病理证实。其中I期12例，II期1例，III期8例，IV期1例。放射剂量超过15 Gy，大多数患者在4至5周内接受40 - 50 Gy的照射。5年无癌生存率为55%（12/22）。I期患者的5年生存率为75%（9/12），III期患者为38%（3/8）。II期和IV期患者均无存活。40 - 50 Gy/4 - 5周的剂量被认为是控制肿瘤的最佳剂量。如果患者存活十年或更长时间，高于60 Gy/6周的剂量可能导致眼眶和颞部骨质结构生长迟缓。
