进一步了解肌原纤维功能在健康和疾病中的作用。
Further progress in understanding of myofibrillar function in health and disease.
机构信息
Department of Pharmacology, School of Medicine, University of Nevada, Reno, Reno, NV.
Cardiovascular Research Center, Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin, Madison, WI.
出版信息
J Gen Physiol. 2021 Jul 5;153(7). doi: 10.1085/jgp.202112972. Epub 2021 Jun 25.
Abstract
The July 2021 issue of is a collection of peer-reviewed articles focused on the function and dynamic regulation of contractile systems in muscle and non-muscle cells.
摘要
2021 年 7 月的《 》是一期同行评议文章合集，聚焦于肌肉和非肌肉细胞中收缩系统的功能和动态调控。
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引用本文的文献
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2022.2022.
J Gen Physiol. 2022 Mar 7;154(3). doi: 10.1085/jgp.202213123. Epub 2022 Feb 18.
本文引用的文献
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Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator.肌球蛋白结合重复蛋白 1（MARP1）将肌联蛋白锁定在肌节细肌丝上，是一种被动力调节蛋白。
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cMyBPC phosphorylation alters response to heart failure drug.cMyBPC 磷酸化改变心力衰竭药物的反应。
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Caldesmon ablation in mice causes umbilical herniation and alters contractility of fetal urinary bladder smooth muscle.钙调蛋白在小鼠中被消融会导致脐疝，并改变胎儿膀胱平滑肌的收缩性。
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Cardiomyopathic mutations in essential light chain reveal mechanisms regulating the super relaxed state of myosin.肌球蛋白调节轻链突变导致的心肌病揭示了调节肌球蛋白超松弛状态的机制。
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Impact of regulatory light chain mutation K104E on the ATPase and motor properties of cardiac myosin.调控轻链突变 K104E 对心肌球蛋白 ATP 酶和运动性质的影响。
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Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle.马卡丹特对兔腰肌和人心肌肌原纤维的收缩力产生不同影响。
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The N2A region of titin has a unique structural configuration.肌联蛋白的 N2A 区域具有独特的结构构象。
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Tubulin acetylation increases cytoskeletal stiffness to regulate mechanotransduction in striated muscle.微管乙酰化增加细胞骨架的刚性，以调节横纹肌中的机械转导。
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