Lopez-Marco Ana, Rosser Barbara, Harky Amer, Verdichizzo Danilo, McPherson Iain, Hope Emma, Qadri Syed, Oo Aung
Department of Cardiothoracic Surgery, St Bartholomew's Hospital, London, United Kingdom.
Department of Cardiothoracic Surgery, Royal Brompton and Harefield NHS Trust, London, United Kingdom.
JTCVS Open. 2021 Mar;5:17-25. doi: 10.1016/j.xjon.2020.11.008. Epub 2020 Nov 26.
The coronavirus disease 2019 (COVID-19) pandemic has posed challenges to health care services across the world. There has been a significant restructuring of health care resources to protect services for patients with COVID-19-related illness and to maintain emergency and urgent medical and surgical activity. This study assessed access to emergency treatment, logistical challenges, and outcomes of patients with acute aortic syndrome during the early months of the COVID-19 pandemic in the United Kingdom.
This was a multicenter study, from March 1 to May 20, 2020 that included 19 cardiac centers, was a retrospective analysis of prospectively collected data obtained from individual centers' national cardiac surgical databases. Demographic details, choice of treatment, operative details, and outcomes were collected. COVID-19 screening, timing of surgery, and outcomes of COVID-19-positive and -negative patients were also analyzed.
In total, 88 patients presented with acute aortic syndrome to participating centers from March 1 to May 20, 2020. There were 79 aortic dissections (89.8%), 7 intramural hematomas (7.9%), and 2 penetrating aortic ulcers (2.3%). Seventy-nine patients (89.8%) underwent surgery. In-hospital mortality was 25.3% (n = 20). Postoperative complications included 13.9% postoperative stroke (11.4% permanent and 2.3% temporary), 16.5% rate of hemofiltration, and 10.1% rate of tracheostomy. Nine patients were treated conservatively with a mortality of 60%. Seven patients were diagnosed with COVID-19, and there was no associated mortality.
Despite extensive restructuring of health care resources, access to emergency and urgent treatment for patients with acute aortic syndrome was maintained in the early months of the COVID-19 pandemic in the United Kingdom. Clinical outcomes were similar to the prepandemic period.
2019年冠状病毒病(COVID-19)大流行给全球医疗服务带来了挑战。为保护COVID-19相关疾病患者的医疗服务,并维持急诊及紧急医疗和外科手术活动,医疗资源进行了重大调整。本研究评估了英国COVID-19大流行最初几个月期间急性主动脉综合征患者的急诊治疗可及性、后勤挑战及治疗结果。
这是一项多中心研究,于2020年3月1日至5月20日开展,纳入了19个心脏中心,对各中心前瞻性收集的来自国家心脏外科数据库的数据进行回顾性分析。收集了人口统计学细节、治疗选择、手术细节及治疗结果。还分析了COVID-19筛查、手术时机以及COVID-19阳性和阴性患者的治疗结果。
2020年3月1日至5月20日期间,共有88例急性主动脉综合征患者到参与研究的中心就诊。其中有79例主动脉夹层(89.8%)、7例壁内血肿(7.9%)和2例穿透性主动脉溃疡(2.3%)。79例患者(89.8%)接受了手术。住院死亡率为25.3%(n = 20)。术后并发症包括13.9%的术后卒中(11.4%为永久性,2.3%为暂时性)、16.5%的血液滤过率和10.1%的气管造口率。9例患者接受保守治疗,死亡率为60%。7例患者被诊断为COVID-19,无相关死亡病例。
尽管医疗资源进行了大规模调整,但在英国COVID-19大流行的最初几个月里,急性主动脉综合征患者仍能获得急诊和紧急治疗。临床结果与大流行前时期相似。