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英国 COVID-19 大流行期间的主动脉手术早期经验:一项多中心研究。

Early experience of aortic surgery during the COVID-19 pandemic in the UK: A multicentre study.

机构信息

Department of Cardiothoracic Surgery, Barts Heart Centre, St. Bartholomew's Hospital, London, UK.

Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.

出版信息

J Card Surg. 2021 Mar;36(3):848-856. doi: 10.1111/jocs.15307. Epub 2021 Jan 13.

Abstract

BACKGROUND

A significant restructuring of the healthcare services has taken place since the declaration of the coronavirus disease 2019 (COVID-19) pandemic, with elective surgery put on hold to concentrate intensive care resources to treat COVID-19 as well as to protect patients who are waiting for relatively low risk surgery from exposure to potentially infected hospital environment.

METHODS

Multicentre study, with 19 participating centers, to define the impact of the pandemic on the provision of aortovascular services and patients' outcomes after having adapted the thresholds for intervention to guarantee access to treatment for emergency and urgent conditions. Retrospective analysis of prospectively collected data, including all patients with aortovascular conditions admitted for surgical or conservative treatment from the 1st March to the 20th May 2020.

RESULTS

A total of 189 patients were analyzed, and 182 underwent surgery. Diagnosis included: aneurysm (45%), acute aortic syndrome (44%), pseudoaneurysm (4%), aortic valve endocarditis (4%), and other (3%). Timing for surgery was: emergency (40%), urgent (34%), or elective (26%). In-hospital mortality was 12%. Thirteen patients were diagnosed with COVID-19 during the peri-operative period, and this subgroup was not associated with a higher mortality.

CONCLUSIONS

There was a significant change in service provision for aortovascular patients in the UK. Although the emergency and urgent surgical activity were maintained, elective treatment was minimal during early months of the pandemic. The preoperative COVID-19 screening protocol, combined with self-isolation and shielding, contributed to the low incidence of COVID-19 in our series and a mortality similar to that of pre-pandemic outcomes.

摘要

背景

自 2019 年冠状病毒病(COVID-19)大流行宣布以来,医疗服务经历了重大重组,选择性手术被搁置,集中重症监护资源治疗 COVID-19 并保护等待相对低风险手术的患者免受潜在感染医院环境的暴露。

方法

多中心研究,有 19 个参与中心,定义大流行对主动脉血管服务提供的影响以及调整干预阈值以保证治疗紧急和紧急情况的患者治疗后结果。回顾性分析前瞻性收集的数据,包括所有在 2020 年 3 月 1 日至 5 月 20 日期间因手术或保守治疗入院的主动脉血管疾病患者。

结果

共分析了 189 例患者,其中 182 例行手术。诊断包括:动脉瘤(45%)、急性主动脉综合征(44%)、假性动脉瘤(4%)、主动脉瓣心内膜炎(4%)和其他(3%)。手术时机为:紧急(40%)、紧急(34%)或择期(26%)。院内死亡率为 12%。13 例患者在围手术期被诊断为 COVID-19,该亚组与更高的死亡率无关。

结论

英国主动脉血管患者的服务提供发生了重大变化。尽管维持了紧急和紧急手术活动,但在大流行的早期几个月,选择性治疗很少。术前 COVID-19 筛查方案,结合自我隔离和屏蔽,有助于降低我们系列中的 COVID-19 发病率和死亡率与大流行前结果相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bec/8013563/4b26a3b1948a/JOCS-36-848-g004.jpg

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