Ehime General Healthcare Association, 1-10-5, Misake-cho, Matsuyama, Ehime, 790-0814, Japan.
Jpn J Radiol. 2021 Dec;39(12):1168-1173. doi: 10.1007/s11604-021-01163-z. Epub 2021 Jun 26.
The purpose of this study was to evaluate the usefulness of single-shot dual-energy subtraction (DES) method using a flat-panel detector for lung cancer screening MATERIALS AND METHODS: The subjects were 13,315 residents (5801 males and 7514 females) aged 50 years or older (50-97 years, with an intermediate value of 68 years) who underwent lung cancer screening for a period of 1 year and 6 months from January 2019 to June 2020. We investigated whether the number of lung cancers detected, the detection rate, and the rate of required scrutiny changed, when DES images were added to the judgment based on conventional chest radiography.
When DES images were added, the number and percentage of cancer detection increased from 16 (0.12%) to 23 (0.17%) (P < 0.05). Five of the newly detected 7 lung cancers were in the early stages of resectable cancer. The rate of participants requiring scrutiny increased slightly from 1.1 to 1.3%.
DES method improved the detection of lung cancer in screening. The increase in the percentage of participants requiring scrutiny was negligible.
本研究旨在评估使用平板探测器进行单次双能量减影(DES)在肺癌筛查中的应用价值。
研究对象为年龄在 50 岁及以上(50-97 岁,中位数为 68 岁)的 13315 名居民(5801 名男性和 7514 名女性),他们在 2019 年 1 月至 2020 年 6 月期间接受了为期 1 年 6 个月的肺癌筛查。我们研究了当在常规胸部 X 线摄影的基础上增加 DES 图像进行判断时,检出肺癌的数量、检出率和需要仔细检查的比例是否发生了变化。
当增加 DES 图像时,癌症检出的数量和百分比从 16 例(0.12%)增加到 23 例(0.17%)(P<0.05)。新检出的 7 例肺癌中有 5 例处于可切除癌症的早期阶段。需要仔细检查的参与者比例从 1.1%略有增加至 1.3%。
DES 方法提高了筛查中肺癌的检出率。需要仔细检查的参与者比例略有增加,但可以忽略不计。