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成人低度脊髓星形细胞瘤的显微外科治疗:个人病例系列报告及文献复习。

MICROSURGICAL MANAGEMENT OF LOW-GRADE SPINAL CORD ASTROCYTOMA IN ADULTS: A PERSONAL CASE SERIES REPORT AND BRIEF LITERATURE REVIEW.

机构信息

1Department of Neurosurgery, University of Marburg, Marburg, Germany; 2Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 3Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 4University of Applied Health Sciences, Zagreb, Croatia; 5School of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 6Semmes-Murphey Neurologic & Spine Institute, Memphis, TN, United States; 7Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN, United States.

出版信息

Acta Clin Croat. 2020 Sep;59(3):505-512. doi: 10.20471/acc.2020.59.03.15.

Abstract

Astrocytoma is the second most common intramedullary tumor of predominantly low-grade malignancy in adult patients. Adult astrocytomas have better-quality prognosis compared with astrocytomas in children. Although a standardized surgical management protocol for spinal cord glioma is currently unavailable, surgery of low-grade astrocytoma should be aimed at gross total resection to preserve neurological function and to improve the outcome. Herein, we present a personal case series of four consecutive adult spinal cord astrocytoma patients who were operated on during the last few years. Tumor resection was performed in all patients utilizing microsurgical technique and intraoperative neurophysiologic monitoring. We also provide a literature review of the treatment of intramedullary astrocytoma in adults and discuss contemporary surgical management and prognosis.

摘要

星形细胞瘤是成人中最常见的第二类主要为低级别恶性的髓内肿瘤。与儿童星形细胞瘤相比,成人星形细胞瘤的预后较好。虽然目前尚无脊髓胶质瘤的标准化手术治疗方案,但低级别星形细胞瘤的手术应旨在实现大体全切除,以保留神经功能并改善预后。在此,我们介绍了过去几年中连续 4 例成人脊髓星形细胞瘤患者的个人病例系列。所有患者均采用显微外科技术和术中神经生理监测进行肿瘤切除。我们还对成人脊髓星形细胞瘤的治疗进行了文献复习,并讨论了当代手术治疗和预后。

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