Nguyen Duc Thuan, Nguyen Quang An, Hoang Thi Dung, Dang Thanh Chung, Le Trung Duc
Department of Neurology, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.
Stroke Center, Phu Tho General Hospital, Phu Tho Province, Vietnam.
Case Rep Neurol. 2021 Jun 1;13(2):318-323. doi: 10.1159/000515156. eCollection 2021 May-Aug.
Foot drop is defined as an impaired ability or inability of dorsiflexion. Peripheral nervous system injuries are commonly considered as the cause of this condition. The central causes including parasagittal meningioma are also described in the literature but very rarely and commonly not recognized early. In this article, we report 2 patients with isolated unilateral foot drop as the first symptom of a parasagittal meningioma and discuss several reasons for delayed diagnosis. Two patients were treated with decompressive craniotomy. The histopathological findings demonstrated a fibroblastic meningioma and a meningothelial meningioma. During postoperative follow-up, the woman patient showed nearly complete recovery and the second case regained total muscle power over a period of 12 months. The rarity of the disease, the absence of upper motor neuron signs, the occurrence of peripheral pathologies and misinterpretation of F wave on nerve conduction study, and motor unit recruitment on electromyography lead to delay in diagnosis and treatment of the central foot drop due to parasagittal meningioma.
足下垂被定义为背屈能力受损或无法背屈。周围神经系统损伤通常被认为是导致这种情况的原因。文献中也描述了包括矢状窦旁脑膜瘤在内的中枢性病因,但非常罕见,且通常不能早期识别。在本文中,我们报告了2例以孤立性单侧足下垂为矢状窦旁脑膜瘤首发症状的患者,并讨论了诊断延迟的几个原因。2例患者均接受了减压开颅手术。组织病理学检查结果显示为纤维母细胞型脑膜瘤和脑膜内皮型脑膜瘤。术后随访期间,女性患者几乎完全康复,第二例患者在12个月内恢复了全部肌肉力量。由于疾病罕见、缺乏上运动神经元体征、周围病变的发生以及神经传导研究中F波的错误解读和肌电图上运动单位募集情况,导致矢状窦旁脑膜瘤所致中枢性足下垂的诊断和治疗延迟。