Valerio Jose, Santiago Noe, Fernandez Gomez Maria P, Rey Martinez Luis, Alvarez-Pinzon Andres M
Neurological Surgery, Palmetto General Hospital, Hialeah, USA.
Neurological Surgery, Larkin Community Hospital, Miami, USA.
Cureus. 2024 Aug 16;16(8):e67029. doi: 10.7759/cureus.67029. eCollection 2024 Aug.
This case report shows the importance of semiology during a clinical examination not only to diagnose spine clinical symptoms but also to review the central nervous system tumor as a foot drop cause. We report a unique case of a patient who consulted for constant progressive numbness and motor symptoms in the right lower extremity. Lumbar CT and MRI were negative for acute or chronic lumbar pathology. This is a 41-year-old female patient with a history of eight-month progressive right leg weakness. The physical examination did not reveal neurological alterations besides foot drop. MRI and lumbar X-rays showed no significant findings. Electromyography (EMG) indicated right peroneal neuropathy. Based on these findings, surgical treatment was not indicated; therefore, physical therapy and a referral to neurology were indicated. However, symptoms increased, resulting in a right lower extremity hemiparesis. A brain MRI showed a left frontoparietal giant meningioma, which was surgically resected after embolization. The patient evolved with a full recovery of the right-sided hemiparesis after surgery. Our case highlights the foot drop's multiple etiologies. Initially, a lumbar disc hernia was suspected, but it was ruled out by imaging studies. Later, the EMG revealed peroneal neuropathy, leading to a neurology consult. Unexpectedly, a giant intracranial meningioma was found, a rare case of foot drop. A consideration of upper motor neuron (UMN) and lower motor neuron (LMN) syndromes aided diagnosis. Tumoral resection with embolization resulted in significant improvement, showcasing the complexities of such cases. Foot drop is a peculiar clinical manifestation that must have an integral assessment to rule out peripheral and central causes. Even rare, giant meningiomas can cause focalized symptoms such as foot drop. Therefore, the assessment of foot drop should include the CT and MRI of the central nervous system.
本病例报告显示了临床检查中症状学的重要性,其不仅有助于诊断脊柱临床症状,还能用于排查中枢神经系统肿瘤作为足下垂病因的可能性。我们报告了一例独特病例,患者因右下肢持续进行性麻木和运动症状前来就诊。腰椎CT和MRI检查未发现急性或慢性腰椎病变。这是一位41岁的女性患者,有8个月进行性右腿无力的病史。体格检查除了足下垂外未发现神经功能改变。MRI和腰椎X线检查均未发现明显异常。肌电图(EMG)显示右腓神经病变。基于这些发现,未建议进行手术治疗;因此,建议进行物理治疗并转诊至神经科。然而,症状加重,导致右下肢偏瘫。脑部MRI显示左侧额顶叶巨大脑膜瘤,在栓塞后进行了手术切除。术后患者右侧偏瘫完全恢复。我们的病例突出了足下垂的多种病因。最初怀疑是腰椎间盘突出症,但影像学检查排除了该诊断。后来,EMG显示腓神经病变,于是转诊至神经科。出乎意料的是,发现了一个巨大的颅内脑膜瘤,这是导致足下垂的罕见病例。对上运动神经元(UMN)和下运动神经元(LMN)综合征的考虑有助于诊断。肿瘤切除并栓塞后病情显著改善,展示了此类病例的复杂性。足下垂是一种特殊的临床表现,必须进行全面评估以排除外周和中枢病因。即使罕见,巨大脑膜瘤也可导致足下垂等局灶性症状。因此,对足下垂的评估应包括中枢神经系统的CT和MRI检查。