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本文引用的文献

1
The use of a poster to reduce expectations to receive antibiotics for a common cold.使用海报来降低对普通感冒开抗生素的期望。
Eur J Clin Microbiol Infect Dis. 2019 Aug;38(8):1463-1469. doi: 10.1007/s10096-019-03572-5. Epub 2019 May 17.
2
Advances in optimizing the prescription of antibiotics in outpatient settings.优化门诊环境下抗生素处方的研究进展。
BMJ. 2018 Nov 12;363:k3047. doi: 10.1136/bmj.k3047.
3
Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis.2015 年欧盟及欧洲经济区因抗生素耐药菌感染导致的死亡人数和伤残调整生命年:基于人群的模型分析。
Lancet Infect Dis. 2019 Jan;19(1):56-66. doi: 10.1016/S1473-3099(18)30605-4. Epub 2018 Nov 5.
4
Antibacterials dispensed in the community comprise 85%-95% of total human antibacterial consumption.社区配发的抗菌药物占人类抗菌药物总消费量的85%-95%。
J Clin Pharm Ther. 2018 Feb;43(1):59-64. doi: 10.1111/jcpt.12610. Epub 2017 Aug 18.
5
Previous antibiotic-related adverse drug reactions do not reduce expectations for antibiotic treatment of upper respiratory tract infections.先前的抗生素相关不良反应并不会降低对上呼吸道感染进行抗生素治疗的期望。
J Glob Antimicrob Resist. 2017 Sep;10:256-260. doi: 10.1016/j.jgar.2017.05.020. Epub 2017 Jul 18.
6
Antibiotics for acute respiratory infections in general practice: comparison of prescribing rates with guideline recommendations.全科医学中急性呼吸道感染的抗生素应用:处方率与指南推荐的比较。
Med J Aust. 2017 Jul 17;207(2):65-69. doi: 10.5694/mja16.01042.
7
Expectations for antibiotics increase their prescribing: Causal evidence about localized impact.对抗生素的期望增加了其处方量:关于局部影响的因果证据。
Health Psychol. 2017 Apr;36(4):402-409. doi: 10.1037/hea0000456. Epub 2017 Feb 16.
8
Why do general practitioners prescribe antibiotics for upper respiratory tract infections to meet patient expectations: a mixed methods study.全科医生为何为上呼吸道感染患者开具抗生素以满足患者期望:一项混合方法研究
BMJ Open. 2016 Oct 24;6(10):e012244. doi: 10.1136/bmjopen-2016-012244.
9
Tipping the Balance Toward Fewer Antibiotics.向减少抗生素使用转变
JAMA Intern Med. 2016 Nov 1;176(11):1649-1650. doi: 10.1001/jamainternmed.2016.6254.
10
Communication practices and antibiotic use for acute respiratory tract infections in children.儿童急性呼吸道感染的沟通方式与抗生素使用
Ann Fam Med. 2015 May-Jun;13(3):221-7. doi: 10.1370/afm.1785.

降低上呼吸道感染患者对抗生素的期望:一项初级保健随机对照试验。

Reducing Expectations for Antibiotics in Patients With Upper Respiratory Tract Infections: A Primary Care Randomized Controlled Trial.

机构信息

Department of Psychological Medicine, University of Auckland, Auckland, New Zealand

Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.

出版信息

Ann Fam Med. 2021 May-Jun;19(3):232-239. doi: 10.1370/afm.2672.

DOI:10.1370/afm.2672
PMID:34180843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8118493/
Abstract

PURPOSE

Many family practitioners prescribe antibiotics for patients with upper respiratory tract infections (URTIs) to meet patients' expectations. We evaluated the impact of providing brief tablet-based information about antibiotic treatment of URTIs on patients' expectations for antibiotics and on family practitioners' antibiotic-prescribing behavior.

METHODS

We performed a 3-arm randomized controlled trial among patients presenting with URTIs at 2 urban family practices in Auckland, New Zealand, during winter 2018. Participants were randomly allocated to view a presentation about the futility of antibiotic treatment of URTIs, the adverse effects associated with antibiotics, or the benefits of healthy diet and exercise (active control), immediately before their consultation. Before and after viewing the presentations, participants used a Likert scale to rate the strength of their belief that antibiotics are effective for treating URTIs and of their desire to be prescribed an antibiotic. Patients reported whether an antibiotic had been prescribed, and pharmacy dispensing records were reviewed to determine whether an antibiotic was dispensed.

RESULTS

Participants who viewed either the futility or the adverse effects presentation had greater reductions in their expectations to receive antibiotics than the control group. The mean reduction (95% CI) was 1.1 (0.8-1.3) for the futility group, 0.7 (0.4-0.9) for the adverse effects group, and 0.1 (0-0.3) for the control group (Cohen = 0.7; <.001). There was no significant difference among the 3 groups with regard to antibiotic prescribing ( = .84) or dispensing ( = .43).

CONCLUSIONS

A brief tablet-based waiting room intervention significantly reduced participants' expectations about receiving antibiotics for URTI immediately before their family practitioner consultation. The intervention did not influence family practitioner prescribing behavior, however.

摘要

目的

许多家庭医生为上呼吸道感染 (URTI) 患者开抗生素,以满足患者的期望。我们评估了提供关于 URTI 抗生素治疗的简短基于平板电脑的信息对患者对抗生素的期望以及对家庭医生开抗生素处方行为的影响。

方法

我们在新西兰奥克兰的 2 家城市家庭实践中进行了一项 3 臂随机对照试验,在 2018 年冬季期间,URTI 患者参与了试验。参与者被随机分配在就诊前立即观看有关抗生素治疗 URTI 无效性、抗生素相关副作用或健康饮食和运动益处的演示(主动对照组)。在观看演示前后,参与者使用李克特量表评估他们对抗生素治疗 URTI 的有效性的信念强度以及他们想要开抗生素的愿望。患者报告是否开了抗生素,并且查看了药房配药记录以确定是否开出了抗生素。

结果

与对照组相比,观看无效或副作用演示的参与者对抗生素的期望降低幅度更大。无效组的平均减少量(95%CI)为 1.1(0.8-1.3),副作用组为 0.7(0.4-0.9),对照组为 0.1(0-0.3)(Cohen = 0.7;<.001)。3 组间抗生素处方(=0.84)或配药(=0.43)无显著差异。

结论

在家庭医生就诊前,简短的基于平板电脑的候诊室干预显著降低了参与者对接受 URTI 抗生素治疗的期望。然而,该干预并未影响家庭医生的处方行为。