Mayer Christian, Khoramnia Ramin
Universitätsaugenklinik Heidelberg, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland.
Ophthalmologe. 2022 Jan;119(1):3-12. doi: 10.1007/s00347-021-01406-4. Epub 2021 Jun 28.
Patients with iris defects suffer from severe visual impairment, especially increased glare sensitivity, and cosmetic disturbances. This can constitute a great psychological strain for patients. In the recent past the treatment consisted of iris print contact lenses, sunglasses and simple iris prostheses. The indications for surgical treatment are colobomas of the iris, aniridia, traumatic iris defects and persistent mydriasis. The aim of this review article is to investigate the surgical approaches, complications, functional and aesthetic outcome after implantation of an individual artificial iris prosthesis made from silicone.
Analysis of the literature on the topic of surgical iris reconstruction with an artificial iris in combination with the own experience in more than 120 patients treated by the author in the last 10 years.
The custom-made flexible silicone iris prosthesis ArtificialIris (HumanOptics, Erlangen, Germany) assessed in this review is an innovative and versatile option for surgical treatment of iris defects. Patients were examined before and after iris reconstruction with respect to feasibility, complications and outcome.
Change of best corrected visual acuity, intraocular pressure, pupillary opening, glare, contrast sensitivity, endothelial cell count, anterior chamber depth, anterior chamber angle and patient satisfaction were assessed. Furthermore, complications and color match to the residual and fellow iris were assessed.
The implantation of an artificial iris is an effective option for the treatment of extensive traumatic iris defects and leads to an individual aesthetically appealing and good functional outcome as well as high patient satisfaction; however, this is an intervention that should not be underestimated because of a flat learning curve and various complications that can occur.
虹膜缺损患者存在严重视力损害,尤其是眩光敏感度增加以及外观缺陷。这会给患者带来巨大的心理压力。过去,治疗方法包括虹膜印记隐形眼镜、太阳镜和简单的虹膜假体。手术治疗的适应证为虹膜缺损、无虹膜、外伤性虹膜缺损和持续性瞳孔散大。本文综述的目的是研究植入由硅胶制成的个体化人工虹膜假体后的手术方法、并发症、功能和美学效果。
结合作者在过去10年中治疗120余例患者的自身经验,分析有关人工虹膜手术重建虹膜这一主题的文献。
本综述中评估的定制柔性硅胶虹膜假体ArtificialIris(德国埃尔兰根HumanOptics公司)是一种用于虹膜缺损手术治疗的创新且通用的选择。在虹膜重建前后对患者进行可行性、并发症和效果方面的检查。
评估了最佳矫正视力、眼压、瞳孔开口、眩光、对比敏感度、内皮细胞计数、前房深度、前房角和患者满意度的变化。此外,还评估了并发症以及与残留虹膜和对侧虹膜的颜色匹配情况。
植入人工虹膜是治疗广泛性外伤性虹膜缺损的有效选择,可带来个体化的美观且功能良好的效果以及较高的患者满意度;然而,由于学习曲线平缓且可能出现各种并发症,这是一种不应被低估的干预措施。