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Reconstructing Phenotypes in Recurrent Severe Wheeze in Young Children.

作者信息

Gaffin Jonathan M

机构信息

Boston Children's Hospital Boston, Massachusetts.

Harvard Medical School Boston, Massachusetts.

出版信息

Am J Respir Crit Care Med. 2021 Sep 1;204(5):495-496. doi: 10.1164/rccm.202105-1294ED.

Abstract
摘要

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本文引用的文献

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Recurrent Severe Preschool Wheeze: From Prespecified Diagnostic Labels to Underlying Endotypes.
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Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze.
J Allergy Clin Immunol. 2019 Apr;143(4):1607-1610.e3. doi: 10.1016/j.jaci.2018.12.985. Epub 2018 Dec 21.
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Severe Asthma Phenotypes - How Should They Guide Evaluation and Treatment?
J Allergy Clin Immunol Pract. 2017 Jul-Aug;5(4):901-908. doi: 10.1016/j.jaip.2017.05.015.
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Individualized therapy for persistent asthma in young children.
J Allergy Clin Immunol. 2016 Dec;138(6):1608-1618.e12. doi: 10.1016/j.jaci.2016.09.028. Epub 2016 Oct 21.
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Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial.
Lancet Respir Med. 2016 Jan;4(1):19-26. doi: 10.1016/S2213-2600(15)00500-7. Epub 2015 Dec 17.
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Classification and pharmacological treatment of preschool wheezing: changes since 2008.
Eur Respir J. 2014 Apr;43(4):1172-7. doi: 10.1183/09031936.00199913. Epub 2014 Feb 13.
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Challenges in identifying asthma subgroups using unsupervised statistical learning techniques.
Am J Respir Crit Care Med. 2013 Dec 1;188(11):1303-12. doi: 10.1164/rccm.201304-0694OC.

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