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莱姆神经Borreliosis 导致单侧小脑炎,表现为 7 岁儿童的水平眼球震颤:一种不常见的眼科表现。

Lyme neuroborreliosis causing unilateral cerebellitis presenting as horizontal nystagmus in a 7-year-old: an unusual presentation to an ophthalmology service.

机构信息

Department of Ophthalmology, Sligo University Hospital, Sligo, Ireland.

Department of Ophthalmology, Sligo University Hospital, Sligo, Ireland.

出版信息

J AAPOS. 2021 Aug;25(4):250-252. doi: 10.1016/j.jaapos.2021.04.006. Epub 2021 Jun 25.

Abstract

Acute cerebellitis is a rare condition with a highly heterogenous clinical course, ranging from self-limiting mild symptoms to a fulminant presentation. Symptoms include headache, vomiting, fever, ataxia, dysarthria, intention tremor, meningism, seizures, and altered level of consciousness. It warrants a high level of suspicion because of the risk of intracranial hypertension and acute hydrocephalus due to compression of the posterior fossa. We present the case of a 7-year-old boy who presented emergently with new-onset left head turn and horizontal nystagmus. Acute inflammation of a single cerebellar hemisphere (hemicerebellitis) in childhood is extremely rare, diagnosed in this case with magnetic resonance imaging. Symmetrical, diffuse cerebellar hemisphere involvement is more typical of cerebellitis. Our patient was unusual in that he presented initially with predominantly ophthalmological signs, with an otherwise normal neurological assessment. Subsequent positive serological Borrelia burgdorferi antibodies led to a diagnosis of Lyme neuroborreliosis.

摘要

急性小脑炎是一种罕见病症,临床表现高度异质,从轻症自限性到暴发性不等。症状包括头痛、呕吐、发热、共济失调、构音障碍、意向性震颤、脑膜刺激征、癫痫发作和意识水平改变。由于后颅窝受压可导致颅内压升高和急性脑积水的风险,因此需要高度怀疑。我们报告了一例 7 岁男孩,突发出现左侧头部转动和水平眼球震颤。儿童单侧小脑半球急性炎症(半脑小脑炎)极为罕见,本病例通过磁共振成像诊断。对称、弥漫性小脑半球受累更常见于小脑炎。我们的患者不寻常之处在于他最初主要表现为眼科征象,而神经系统检查其他方面正常。随后的伯氏疏螺旋体血清学阳性抗体导致莱姆神经Borreliosisosis 病的诊断。

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