Northern Forensic Pathology Service of New Zealand, Auckland, New Zealand.
Forensic and Analytical Science Service, NSW Health Pathology, Sydney, New South Wales, Australia.
Auton Neurosci. 2021 Sep;234:102837. doi: 10.1016/j.autneu.2021.102837. Epub 2021 Jun 24.
Sudden cardiac death (SCD) is the most common natural cause of death. The hypothesized mechanism of death is an arrhythmia precipitated by increased sympathetic outflow. The left stellate ganglion provides sympathetic innervation to the heart and plays a role in arrhythmogensis. We present a SCD with stellate ganglionitis in which the inflammatory cells were characterized. The case was 37-year-old man who died from ischemic and hypertensive heart disease. The left stellate ganglion showed lymphocytic inflammation with features of humoral immune response. This case report provides evidence that stellate ganglionitis can be seen in SCD and raises the possible association between the two.
心源性猝死(SCD)是最常见的自然死亡原因。推测的死亡机制是交感神经输出增加引发的心律失常。左侧星状神经节为心脏提供交感神经支配,并在心律失常发生中起作用。我们报告了一例伴有星状神经节炎的 SCD 病例,其中炎症细胞的特征如下。该病例为一名 37 岁男性,死于缺血性和高血压性心脏病。左侧星状神经节表现为淋巴细胞炎症,具有体液免疫反应的特征。本病例报告提供了证据表明,SCD 中可出现星状神经节炎,并提示两者之间可能存在关联。