微脉冲经巩膜睫状体光凝术后眼压降低与前房房水闪辉的相关性。
Correlation between intraocular pressure reduction and anterior chamber aqueous flare after micropulse transscleral cyclophotocoagulation.
机构信息
Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto, Japan.
出版信息
BMC Ophthalmol. 2021 Jun 29;21(1):266. doi: 10.1186/s12886-021-02012-3.
BACKGROUND
Micropulse transscleral cyclophotocoagulation (MP-CPC) is a technique that has been approved in recent years to treat glaucoma. MP-CPC causes anterior chamber inflammation; a relationship with reduced intraocular pressure (IOP) has not been reported. Therefore, we analyzed the correlation between IOP and anterior chamber aqueous flare after MP-CPC.
METHODS
This retrospective study included 37 eyes of 37 patients who underwent MP-CPC between November 2018 and October 2020. IOP and flare values were measured at 1, 4, and 12 weeks after MP-CPC. Correlations were assessed between the percentage IOP reduction and flare elevation by calculating Spearman's rank correlation coefficient.
RESULTS
The percentage IOP reduction at 1 week after surgery was correlated with the flare elevation at 1 week after surgery (ρ = 0.47, P = 0.006). The percentage IOP reduction at 12 weeks after surgery was correlated with the flare elevation at 4 weeks after surgery (ρ = 0.53, P = 0.006).
CONCLUSIONS
A short-term correlation was implied between reduced IOP and flare elevation after MP-CPC.
背景
微脉冲经巩膜睫状体光凝术（MP-CPC）是近年来被批准用于治疗青光眼的一种技术。MP-CPC 会引起前房炎症，但与眼压降低之间的关系尚未有报道。因此，我们分析了 MP-CPC 后眼压与前房房水闪辉之间的相关性。
方法
本回顾性研究纳入了 2018 年 11 月至 2020 年 10 月期间接受 MP-CPC 治疗的 37 例 37 只眼。在 MP-CPC 后 1、4 和 12 周测量眼压和闪辉值。通过计算 Spearman 秩相关系数评估眼压降低百分比与闪辉升高之间的相关性。
结果
术后 1 周的眼压降低百分比与术后 1 周的闪辉升高呈正相关（ρ=0.47，P=0.006）。术后 12 周的眼压降低百分比与术后 4 周的闪辉升高呈正相关（ρ=0.53，P=0.006）。
结论
MP-CPC 后眼压降低与闪辉升高之间存在短期相关性。
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