From the Departments of Nuclear Medicine and Molecular Imaging.
Radiation Oncology, Tata Memorial Center, Homi Bhabha National Institute, Mumbai, India.
Clin Nucl Med. 2022 Jan 1;47(1):e108-e110. doi: 10.1097/RLU.0000000000003788.
Medulloblastomas, especially the sonic hedgehog subgroup, are treated aggressively with surgery and chemoradiotherapy, as they are associated with high local site recurrence rate and poor overall survival. Radiation-induced meningioma is the most common delayed complication of craniospinal irradiation. This needs to be differentiated from meningeal or ependymal metastases as the later need aggressive management. We report one such rare case, in a patient who completed treatment for medulloblastoma 11 years ago, was in remission, and now presented with dural-based lesions.
髓母细胞瘤,尤其是 sonic hedgehog 亚组,采用手术和放化疗积极治疗,因为它们与局部复发率高和整体生存率差相关。放射性脑膜瘤是颅脑照射最常见的迟发性并发症。这需要与脑膜或室管膜转移相区别,因为后者需要积极治疗。我们报告了这样一个罕见病例,患者 11 年前完成了髓母细胞瘤治疗,处于缓解期,现在出现了基于硬脑膜的病变。