Department of Medical Education, University of Melbourne.
College of Health & Biomedicine, Victoria University.
Clin J Pain. 2021 Sep 1;37(9):639-647. doi: 10.1097/AJP.0000000000000955.
Musculoskeletal pain is a significant contributor to the global disease burden. Management of musculoskeletal pain where a neuropathic component is present can be challenging. This study evaluated the internal structure of the Patient-Reported Outcome Measures Information System (PROMIS) pain quality scales, explored the prevalence of neuropathic and nociceptive pain, and identified health demographics and behaviors related to musculoskeletal pain presentations.
Patients presenting to the Victoria University Osteopathy Clinic (Melbourne, Vic., Australia) were invited to complete a health demographics and behaviors questionnaire, and the PROMIS Neuropathic (NeuroPQ) and Nociceptive (NociPQ) pain quality scales, before their initial consultation. Descriptive, inferential, and correlation statistics were used to evaluate the PROMIS scales, health demographics, and behaviors. Mokken scale analysis was used to evaluate the internal structure and dimensionality of the NeuroPQ and NociPQ scales.
Three hundred eighty-three (N=383) patients completed the measures. Mokken scaling suggested the PROMIS scales demonstrated acceptable internal structure and were unidimensional. Over 22% of patients demonstrated cutoff scores above 50, suggesting a substantive neuropathic pain component to their musculoskeletal presentation. Patients who reported cigarette smoking, not being born in Australia or not speaking English at home, demonstrated higher NeuroPQ scores. Females demonstrated significantly higher NociPQ scores than males. Pain intensity demonstrated small to medium correlations with NeuroPQ and NociPQ scores.
This study provides support for the use of the NeuroPQ and NociPQ scales in musculoskeletal pain patients. Associations with health demographics and behaviors were identified, and patients typically experienced a combination of neuropathic and nociceptive pain.
肌肉骨骼疼痛是全球疾病负担的一个重要因素。存在神经病理性成分的肌肉骨骼疼痛的管理具有挑战性。本研究评估了患者报告的结局测量信息系统（PROMIS）疼痛质量量表的内部结构，探讨了神经病理性和伤害感受性疼痛的患病率，并确定了与肌肉骨骼疼痛表现相关的健康人口统计学和行为。
维多利亚大学整骨诊所（澳大利亚墨尔本）的患者在首次就诊前被邀请完成健康人口统计学和行为问卷以及 PROMIS 神经病理性（NeuroPQ）和伤害感受性（NociPQ）疼痛质量量表。使用描述性、推论性和相关性统计数据来评估 PROMIS 量表、健康人口统计学和行为。Mokken 量表分析用于评估 NeuroPQ 和 NociPQ 量表的内部结构和维度。
383 名（N=383）患者完成了这些措施。Mokken 定序表明，PROMIS 量表表现出可接受的内部结构和单维性。超过 22%的患者表现出高于 50 的截断分数，表明他们的肌肉骨骼表现存在实质性的神经病理性疼痛成分。报告吸烟、不是在澳大利亚出生或在家不说英语的患者表现出更高的 NeuroPQ 分数。女性的 NociPQ 评分明显高于男性。疼痛强度与 NeuroPQ 和 NociPQ 评分呈小到中等相关性。
本研究为在肌肉骨骼疼痛患者中使用 NeuroPQ 和 NociPQ 量表提供了支持。确定了与健康人口统计学和行为的关联，并且患者通常经历神经病理性和伤害感受性疼痛的组合。
