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[一种预测良性阵发性位置性眩晕后功能性头晕的方法]

[A method for prediction functional dizziness after benign paroxysmal positional vertigo].

作者信息

Dyukova G M, Kryukov A I, Makarov S A, Guseva A L, Olimpieva S P

机构信息

Loginov Moscow Clinical Scientific and Practical Center Moscow, Russi, Loginov Moscow Clinical Scientific and Practical Center Moscow, Russia.

Pirogov Russian National Research Medical University, Moscow, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(5):120-125. doi: 10.17116/jnevro2021121051120.

Abstract

OBJECTIVE

To identify risk factors for functional vertigo (FV) in patients with benign paroxysmal positional vertigo (BPPV) based on the analysis of emotional and personality disorders at the time of the occurrence of BPPV and to develop a method for predicting its development.

MATERIAL AND METHODS

The study included 93 people, 81 women (87.1%), with benign paroxysmal positional vertigo (BPPV), aged 18 to 65 years, mean age 50 [41.5; 59]). After successful treatment with repositioning maneuvers, patients were re-examined 1 month later. Fifty-three patients underwent a semi-structured interview to identify a history of panic attacks (PA) using DSM-5 diagnostic criteria. After successful BPPV treatment, patients completed the following scales and questionnaires: Dizziness Handicap Inventory (DHI), Vertigo Symptom Scale Short form (VSS-SF), Numeric analog scale of fear (from 0 to 10), Depersonalization-Derealization Inventory (DDI), PHQ-9, GAD-7, PHQ-15, Holmes-Rahe Stress Inventory, Anxiety Sensitivity Index (ASI).

RESULTS

The cohort was divided into two groups according to the presence (group 1, =17) or absence (group 2, =76) of complaints for dizziness 1 month after BPPV. The frequency of PA history in group 1 was higher than in group 2 (80 vs 29.3%). Patients from group 1 had higher rates in all scales: DHI (57 vs 49, =0.048), subscale DHI-E (18 vs 12, =0.006), and subscale A VSS-SF (9 vs 5, =0.03); DDI (18 vs 11, =0.01), GAD-7 (13 vs 4), =0.0002), Numeric analog scale of fear (10 vs 5, <0.00005), ASI (55.5 vs 36.5, <0.005). We developed a predictive method for diagnosis FD after BPPV, which sensitivity is 78.9% (95% CI 67.80-86.94) and specificity 94.12% (95% CI 71.31-99.85).

CONCLUSION

The likelihood of developing FV after BPPV can be predicted using the proposed predictive method. Early screening for FV can be used to prevent persistent postural-perceptual dizziness.

摘要

目的

通过分析良性阵发性位置性眩晕(BPPV)发作时的情绪和人格障碍,确定BPPV患者发生功能性眩晕(FV)的危险因素,并开发一种预测其发展的方法。

材料与方法

该研究纳入了93人,其中81名女性(87.1%),年龄在18至65岁之间,平均年龄50岁[41.5;59]),患有良性阵发性位置性眩晕(BPPV)。在通过复位手法成功治疗后,患者在1个月后接受复查。53名患者接受了半结构式访谈,以使用DSM-5诊断标准确定惊恐发作(PA)史。在BPPV成功治疗后,患者完成了以下量表和问卷:头晕残障量表(DHI)、眩晕症状量表简表(VSS-SF)、恐惧数字模拟量表(0至10)、人格解体-现实解体量表(DDI)、PHQ-9、GAD-7、PHQ-15、霍尔姆斯-拉赫压力量表、焦虑敏感性指数(ASI)。

结果

根据BPPV后1个月是否存在头晕主诉,将该队列分为两组(第1组,n = 17;第2组,n = 76)。第1组的PA病史发生率高于第2组(80%对29.3%)。第1组患者在所有量表上的得分均较高:DHI(57对49,P = 0.048)、DHI-E子量表(18对12,P = 0.006)和VSS-SF A子量表(9对5,P = 0.03);DDI(18对11,P = 0.01)、GAD-7(13对4,P = 0.0002)、恐惧数字模拟量表(10对5,P < 0.00005)、ASI(55.5对36.5,P < 0.005)。我们开发了一种BPPV后诊断FD的预测方法,其敏感性为78.9%(95%CI 67.80 - 86.94),特异性为94.12%(95%CI 71.31 - 99.85)。

结论

使用所提出的预测方法可以预测BPPV后发生FV的可能性。对FV进行早期筛查可用于预防持续性姿势性感知性头晕。

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