Chukhlovina M L
Almazov National Medical Research Center, St. Petersburg, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(5):138-143. doi: 10.17116/jnevro2021121051138.
Our review article aimed for analysis of pathogenesis, diagnostyics and treatment of polyneuropathies manifesting in the course of COVID-19. The reasons for hyposmia and taste disturbances are considered in the subjects with this coronavirus infection as well as relationship between these clinical manifestations and severity of the viral infection. Special attention is given to description of autoimmune mechanisms of GuillainBarré syndrome and polyneuropathies of critical conditions associated with COVID-19. Some data report about clinical deterioration of diabetic and alcoholic neuropathy during the SARS-CoV-2 infection. Inclusion of group B vitamins, together with C and D vitamins, is recommended to the schedules of combined treatment for polyneuropathies in these patients. Early diagnostics of polyneuropathies, especially, GuillainBarré syndrome, is required during COVID-19 pandemics, thus helping to administer rational therapy and promoting better quality of life in the patients.
我们的综述文章旨在分析新型冠状病毒肺炎（COVID-19）病程中出现的多发性神经病的发病机制、诊断方法和治疗。本文还探讨了感染这种冠状病毒的患者出现嗅觉减退和味觉障碍的原因，以及这些临床表现与病毒感染严重程度之间的关系。特别关注格林-巴利综合征的自身免疫机制以及与COVID-19相关的危重症多发性神经病的描述。一些数据报告了严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染期间糖尿病性和酒精性神经病的临床恶化情况。建议在这些患者多发性神经病的联合治疗方案中加入B族维生素以及维生素C和D。在COVID-19大流行期间，需要早期诊断多发性神经病，尤其是格林-巴利综合征，这有助于实施合理治疗并提高患者的生活质量。
