Department of Orthopedics, Shangqiu Yadong Hospital, Shangqiu, China.
University Hospital Cologne, University of Cologne, Cologne, Germany.
Br J Neurosurg. 2023 Dec;37(6):1843-1849. doi: 10.1080/02688697.2021.1940861. Epub 2021 Jun 29.
Charcot arthropathy, also known as neuropathic arthropathy, is a rare disease whose early diagnosis and treatment are very difficult. Generally, diabetes is considered the most common cause of Charcot arthropathy. Although Charcot arthropathy of other secondary etiology has been reported, in most cases only a single joint is accumulated, and rarely involving the feet and shoulders. Clinically, Charcot arthropathy due to delayed diagnosis leads to joint destruction and severe cases abound.
What we report is an unprecedented case, in which the patient was diagnosed as left shoulder joint, interdigital joint Charcot arthropathy caused by cervical spondylotic myelopathy (CSM) and left knee and right ankle Charcot arthropathy caused by adult degenerative scoliosis (ADS) complicated by syringomyelia. The 82-year-old male patient was admitted to the hospital for complaining of pain in the left knee joint. Except for scoliosis that was discovered 10 years ago, the patient denied any other obvious past medical history. Clinical/surgical manifestations, detailed physical examinations and auxiliary examinations all indicated the presence of polyarticular Charcot arthropathy, but common causes of Charcot arthropathy such as diabetes and syphilis have not been detected. After making a comprehensive differential diagnosis, we finally made the above diagnosis.
This previously unreported case describes the complexity and etiological diversity of Charcot arthropathy. We recommend that patients with CSM and/or scoliosis, spinal deformity undergo further examination and regular follow-up. A detailed medical history and careful physical examination are necessary for the correct diagnosis of Charcot arthropathy. Although the early diagnosis of Charcot arthropathy cannot change the natural course of the disease, it is beneficial to alleviate symptoms and prevent serious complications.
夏科氏关节病,又称神经病变性关节病,是一种罕见疾病,早期诊断和治疗非常困难。一般认为糖尿病是夏科氏关节病最常见的病因。虽然已有其他继发病因引起的夏科氏关节病的报道,但在大多数情况下,仅单个关节受累,且很少累及足部和肩部。临床上,由于夏科氏关节病诊断延迟,导致关节破坏,严重病例较多。
我们报告的是一个前所未有的病例,患者被诊断为颈椎病性脊髓病(CSM)引起的左侧肩关节、指间关节夏科氏关节病和成人退行性脊柱侧凸(ADS)引起的左侧膝关节和右侧踝关节夏科氏关节病,并伴有脊髓空洞症。这名 82 岁男性患者因左膝关节疼痛入院。除了 10 年前发现的脊柱侧凸外,患者否认有任何其他明显的既往病史。临床/手术表现、详细的体格检查和辅助检查均表明存在多关节夏科氏关节病,但未发现糖尿病和梅毒等常见夏科氏关节病的病因。经过全面鉴别诊断,我们最终做出了上述诊断。
这个以前没有报道过的病例描述了夏科氏关节病的复杂性和病因多样性。我们建议 CSM 和/或脊柱侧凸、脊柱畸形患者进行进一步检查和定期随访。详细的病史和仔细的体格检查对于夏科氏关节病的正确诊断是必要的。虽然夏科氏关节病的早期诊断不能改变疾病的自然病程,但有利于缓解症状和预防严重并发症。