Wang Xin, Li Yongning, Gao Jun, Wang Tianyu, Li Zhimin
Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Medicine (Baltimore). 2018 Jul;97(28):e11391. doi: 10.1097/MD.0000000000011391.
Charcot arthropathy, also known as Neuropathic arthropathy (NA), is an unusual chronic degenerative disease. To date, there exists a paucity of research on NA caused by syringomyelia.
A 52-year-old non-diabetic female presented with progressive swelling, pain and limited movement in her left shoulder joint combined with asthenia of her left upper extremity for three months.
Neuropathic arthropathy of the shoulder associated with the cervicothoracic syrinx and basilar impressions was diagnosed.
The treatment is directed to its potential cause to cease its progression. A posterior fossa decompression (PFD) was conducted for this patient.
Postoperatively, the patient's symptoms were relieved and the size of syrinx was reduced at the 6-month follow-up.
Taken together with 34 previous reports identified from a PubMed search, an analysis of 35 cases of Charcot arthropathy was conducted. Surgical decompression is an effective treatment, but the optimal treatment remains controversial. Thus, the aim of this literature review was to remind us to diagnose the potential cause as early as possible and we should spare no efforts on the exploration of etiology and adjuvant therapy for this disease.
夏科氏关节病，也称为神经性关节病（NA），是一种罕见的慢性退行性疾病。迄今为止，关于脊髓空洞症所致NA的研究较少。
一名52岁非糖尿病女性，出现左肩渐进性肿胀、疼痛、活动受限，伴左上肢乏力3个月。
诊断为与颈胸段脊髓空洞症及颅底凹陷相关的肩部神经性关节病。
治疗针对其潜在病因以阻止病情进展。对该患者实施了后颅窝减压术（PFD）。
术后6个月随访时，患者症状缓解，脊髓空洞体积缩小。
结合从PubMed检索中确定的34篇既往报告，对35例夏科氏关节病进行了分析。手术减压是一种有效的治疗方法，但最佳治疗方案仍存在争议。因此，这篇文献综述的目的是提醒我们尽早诊断潜在病因，并且应不遗余力地探索该疾病的病因及辅助治疗方法。
