[垂体切除及注射生长激素后胰腺岛状结构的形态功能变化]
[Morphofunctional changes in the insular apparatus of the pancreas following hypophysectomy and administration of somatotropic hormone].
作者信息
Shevchuk I A, Kovtuniak N A, Iarmol'chuk G M, Panchuk N N
出版信息
Arkh Anat Gistol Embriol. 1977 Dec;73(12):68-72.
Mature white male rats were used to study effects of hypophysectomy and STH on sugar content after fasting and after reiterated glucose loading. Morphological and morphometrical investigation of the pancreatic endocrine tissue were made. Zinc content and distribution in the pancreas, as well as aldehydefuchsinophil granulation in B-cells of the islets of Langergans were studied. Hypophysectomy was stated to increase functional activity of the pancreatic insular apparatus. Injection of STH for 9 days resulted in the stimulation of the cells in the insular apparatus. Prolonged injection of STH (for 20 days) produced exhaustion of the pancreatic insular apparatus.
成熟的雄性白色大鼠被用于研究垂体切除和生长激素对禁食后及反复葡萄糖负荷后糖含量的影响。对胰腺内分泌组织进行了形态学和形态计量学研究。研究了胰腺中的锌含量和分布，以及朗格汉斯岛胰岛B细胞中的嗜品红醛颗粒。据指出，垂体切除会增加胰腺胰岛装置的功能活性。注射生长激素9天会刺激胰岛装置中的细胞。长期注射生长激素（20天）会导致胰腺胰岛装置耗竭。
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