Frank R G, Beck N C, Parker J C, Kashani J H, Elliott T R, Haut A E, Smith E, Atwood C, Brownlee-Duffeck M, Kay D R
Multipurpose Arthritis Center, School of Medicine, University of Missouri-Columbia.
J Rheumatol. 1988 Jun;15(6):920-5.
Operationalized diagnostic criteria for depression were used to assess 137 (76% male, 24% female) patients with rheumatoid arthritis (RA). Forty-two percent met criteria for some form of depression. Discriminant function analysis revealed a significant relationship between the presence or history of depression and higher levels of pain, but not between current depression and common indicators of RA activity or severity. These results suggest that depression is a frequent disorder among persons with RA. The importance of patient appraisal of disease and assessment of repeated depressive episodes is discussed. Attention to specific interventions for depression in conjunction with the treatment of the RA is suggested.
采用抑郁的操作性诊断标准对137例类风湿关节炎（RA）患者进行评估（其中男性占76%，女性占24%）。42%的患者符合某种形式的抑郁标准。判别函数分析显示，抑郁的存在或病史与较高水平的疼痛之间存在显著关系，但当前抑郁与RA活动或严重程度的常见指标之间不存在显著关系。这些结果表明，抑郁在RA患者中是一种常见疾病。文中讨论了患者对疾病评估及反复抑郁发作评估的重要性。建议在治疗RA的同时关注针对抑郁的具体干预措施。
