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上颌骨和颞骨转移性肝细胞癌:一例罕见病例报告

Metastatic hepatocellular carcinoma in the maxilla and temporal bone: a rare case report.

作者信息

Cho Juyeon

机构信息

Department of Dentistry, Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2021 Jun 30;47(3):224-228. doi: 10.5125/jkaoms.2021.47.3.224.

DOI:10.5125/jkaoms.2021.47.3.224
PMID:34187963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8249191/
Abstract

Hepatocellular carcinoma (HCC) is a common, primary malignant liver disease that usually metastasizes to the lungs, followed by the abdominal lymph nodes and brain. However, extrahepatic metastasis to the maxillofacial area is uncommon and predominates in the mandible, so HCCs in the maxilla or temporal bone from a primary hepatic lesion are extremely rare. We present a case of HCC in the maxilla and temporal bone in a 52-year-old male, which was first suspected to be a squamous cell carcinoma after computed tomography but was confirmed as a metastasis related to his primary HCC after fine-needle aspiration biopsy followed by immunohistochemical analysis.

摘要

肝细胞癌(HCC)是一种常见的原发性肝脏恶性疾病,通常转移至肺部,其次是腹部淋巴结和脑部。然而,HCC向颌面区域的肝外转移并不常见,且以下颌骨为主,因此源于原发性肝脏病变的上颌骨或颞骨HCC极为罕见。我们报告一例52岁男性上颌骨和颞骨的HCC病例,该病例在计算机断层扫描后最初怀疑为鳞状细胞癌,但在细针穿刺活检及免疫组化分析后确诊为与原发性HCC相关的转移瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/f8a45ed02e97/jkaoms-47-3-224-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/8a1404421d64/jkaoms-47-3-224-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/ed8c022dc49b/jkaoms-47-3-224-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/62276f7bb762/jkaoms-47-3-224-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/236e63adfe73/jkaoms-47-3-224-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/f8a45ed02e97/jkaoms-47-3-224-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/8a1404421d64/jkaoms-47-3-224-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/ed8c022dc49b/jkaoms-47-3-224-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/62276f7bb762/jkaoms-47-3-224-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/236e63adfe73/jkaoms-47-3-224-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab9/8249191/f8a45ed02e97/jkaoms-47-3-224-f5.jpg

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BMC Cancer. 2019 Sep 14;19(1):925. doi: 10.1186/s12885-019-6020-7.
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Zygomatic bone metastasis from hepatocellular carcinoma and the therapeutic efficacy of apatinib: A case report and literature review.肝细胞癌颧骨转移及阿帕替尼的治疗效果:一例报告及文献复习
Medicine (Baltimore). 2019 May;98(18):e14595. doi: 10.1097/MD.0000000000014595.
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Epidemiology of hepatocellular carcinoma: target population for surveillance and diagnosis.
肝细胞癌的流行病学:监测和诊断的目标人群。
Abdom Radiol (NY). 2018 Jan;43(1):13-25. doi: 10.1007/s00261-017-1209-1.
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Hepatocellular carcinoma: From diagnosis to treatment.肝细胞癌:从诊断到治疗
Surg Oncol. 2016 Jun;25(2):74-85. doi: 10.1016/j.suronc.2016.03.002. Epub 2016 Mar 5.
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Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation.上颌骨和下颌骨转移性肝细胞癌,一种极其罕见的表现。
Contemp Clin Dent. 2015 Mar;6(Suppl 1):S117-21. doi: 10.4103/0976-237X.152966.
6
Zygomatic bone metastasis as an initial presentation of hepatocellular carcinoma.颧骨转移作为肝细胞癌的首发表现
Arch Iran Med. 2013 Nov;16(11):675-8.
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Hepatocellular carcinoma metastasis to the maxilla: a rare case.肝细胞癌转移至上颌骨:一例罕见病例。
Aust Dent J. 2013 Sep;58(3):373-5. doi: 10.1111/adj.12083. Epub 2013 Jul 24.
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