Department of Anaesthesiology and Intensive Care Medicine, University Hospital Magdeburg, Magdeburg 39120, Germany.
Augenzentrum Leiterstrasse, Magdeburg 39104, Germany.
Pain Res Manag. 2021 Jun 3;2021:5515629. doi: 10.1155/2021/5515629. eCollection 2021.
It is well known that cancer patients more seldom have a psychiatric disorder than noncancer patients with chronic pain. Conversely, earlier studies have suggested that, at the psychiatric level, long-term cancer survivors (LCSs) have more in common with noncancer patients affected by chronic pain.
We investigated 89 cancer patients with acute pain (Acute Cancer Pain Patients, ACPPs) treated at a university outpatient chemotherapy department and compared these with 61 LCSs (living >5 yr after the first diagnosis) admitted by general practitioners for the treatment of noncancer pain. Upon administration, each patient was psychiatrically assessed by a liaison-psychiatrist conducting a semistructured interview. In a second step, we compared the LCS patients with hitherto treated noncancer patients suffering from chronic pain and ACPPs with data published by Derogatis in 1983.
In a comparison of LCSs with ACPPs, LCSs have more patients with brain organic disorders and more addictions. The largest cancer group within the LCSs is patients with urogenital (Uro) cancer (44.3%), while within the ACPPs, these are patients with cancer of the gastrointestinal (GI) tract (ACPP-GI, 57.2%). As far as the distribution of mental disorders is concerned, long-term cancer survivors show some similarities to noncancer patients. The data of ACPPs are similar to those of cancer patients, published by Derogatis. . The higher values of addiction and brain organic disorders, in particular, and the slight differences for psychic disorders in general of LCSs vs. ACPPs may result from the different cancer types and a longer survival time for urogenital tract cancer compared to GI cancer. In an additional examination, we compared patients with acute cancer of the GI tract (ACPP-GI, = 50) with those of the urogenital tract (ACPP-Uro, = 43). ACPP-Uro had the lowest percentage of patients with psychiatric disorders in general (ACPP-Uro 37.2%, ACPP-GI 50.0%, all LCSs 65.6%, and LCS-Uro 74.1%) and addiction, in particular (ACPP-Uro 2.3%, ACPP-GI 4.0%, and LCSs 13.1%).
Cancer patients can develop a process of chronification with an increase in the prevalence of mental disorders. For urogenital cancer, an increase in the probability to develop mental disorders is a function of time.
众所周知，癌症患者患精神障碍的比例比患有慢性疼痛的非癌症患者低。相反，早期的研究表明，在精神层面上，长期癌症幸存者（LCSs）与受慢性疼痛影响的非癌症患者更为相似。
我们调查了在大学门诊化疗部门接受治疗的 89 名急性疼痛癌症患者（急性癌症疼痛患者，ACPPs），并将这些患者与因非癌症疼痛接受全科医生治疗的 61 名 LCSs（首次诊断后存活>5 年）进行了比较。每位患者入院时都由一名联络精神科医生进行半结构化访谈进行精神评估。在第二步中，我们将 LCS 患者与迄今为止接受慢性疼痛治疗的非癌症患者和 Derogatis 于 1983 年发表的 ACPP 患者进行了比较。
将 LCSs 与 ACPPs 进行比较，LCSs 中脑器质性疾病和成瘾患者更多。LCSs 中最大的癌症组是泌尿系统（Uro）癌症患者（44.3%），而在 ACPPs 中，这些患者是胃肠道（GI）癌症患者（ACPP-GI，57.2%）。就精神障碍的分布而言，长期癌症幸存者与非癌症患者有一些相似之处。ACPPs 的数据与 Derogatis 发表的癌症患者数据相似。LCSs 与 ACPPs 相比，成瘾和脑器质性疾病的比例较高，一般来说，精神障碍的差异较小，这可能是由于不同的癌症类型以及与胃肠道癌症相比，泌尿系统癌症的生存时间较长所致。在进一步的检查中，我们比较了患有胃肠道癌症的急性癌症患者（ACPP-GI，n=50）和患有泌尿系统癌症的急性癌症患者（ACPP-Uro，n=43）。ACPP-Uro 患者总体上患有精神障碍的比例最低（ACPP-Uro 37.2%，ACPP-GI 50.0%，所有 LCSs 65.6%，LCS-Uro 74.1%），尤其是成瘾比例最低（ACPP-Uro 2.3%，ACPP-GI 4.0%，LCSs 13.1%）。
癌症患者可能会出现慢性化过程，精神障碍的患病率增加。对于泌尿系统癌症，精神障碍发生概率的增加是时间的函数。
