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子宫动脉栓塞术联合甲氨蝶呤治疗一名30岁初孕妇的阔韧带异位妊娠

Uterine artery embolization combined with methotrexate for broad ligament ectopic pregnancy in a 30-year old primigravida.

作者信息

Bhinder Khurram Khaliq, Sarfraz Azza, Sarfraz Zouina, Riaz Shaista, Aslam Samreen, Ameena Zouina

机构信息

Shifa International Hospital, Islamabad, Pakistan.

The Aga Khan University, Karachi, Pakistan.

出版信息

Radiol Case Rep. 2021 Jun 15;16(8):2248-2251. doi: 10.1016/j.radcr.2021.05.032. eCollection 2021 Aug.

DOI:10.1016/j.radcr.2021.05.032
PMID:34188737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8217555/
Abstract

We present the case of 30-year old primigravida female at 11 weeks' gestation who was diagnosed to have ectopic pregnancy on obstetric ultrasound. An MRI pelvis was ordered to assess invasion into the posterior myometrium which confirmed a single right-sided broad ligament-extra uterine pelvic ectopic pregnancy with extrinsic mass effect on the right lower uterine segment without frank myometrial invasion. On an urgent basis, a uterine artery embolization (UAE) was performed by targeting the right femoral artery. Selective catheterization was performed of both uterine arteries and the right side showed a major feeder of the gestational sac. Supplied dose of methotrexate (95mg) was infused in the right uterine artery and both arteries were then embolized by gel foam slurry. Thus, prompt treatment reduced the risk of infertility and saved the patient from obstetrical emergency. Further exploration needs to be done in this field to explore conservative management options to preserve fertility.

摘要

我们报告一例30岁初产妇,孕11周,经产科超声诊断为异位妊娠。行盆腔MRI检查以评估对子宫后壁肌层的侵犯情况,结果证实为右侧阔韧带-子宫外盆腔单发性异位妊娠,对子宫下段右侧有外在肿块效应,但无明显子宫肌层侵犯。在紧急情况下,通过靶向右侧股动脉进行了子宫动脉栓塞术(UAE)。对双侧子宫动脉进行了选择性插管,右侧显示为妊娠囊的主要供血支。将95mg甲氨蝶呤的给药剂量注入右侧子宫动脉,然后用明胶海绵浆液栓塞双侧动脉。因此,及时的治疗降低了不孕风险,使患者免于产科急症。该领域需要进一步探索以寻求保留生育能力的保守治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e5/8217555/db38ea1a4adf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e5/8217555/2453a91f604f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e5/8217555/db38ea1a4adf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e5/8217555/2453a91f604f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e5/8217555/db38ea1a4adf/gr2.jpg

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本文引用的文献

1
Broad ligament pregnancy: A case series and literature review.阔韧带妊娠:病例系列及文献复习。
J Obstet Gynaecol Res. 2021 Jan;47(1):442-445. doi: 10.1111/jog.14564. Epub 2020 Nov 20.
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Laparoscopic Management of Abdominal Pregnancy.腹腔镜下处理腹腔妊娠
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Broad Ligament Pregnancy - Success Story of a Laparoscopically Managed Case.阔韧带妊娠——腹腔镜治疗病例的成功故事。
J Clin Diagn Res. 2016 Jul;10(7):QD04-5. doi: 10.7860/JCDR/2016/19293.8136. Epub 2016 Jul 1.
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Uterine artery embolization for cervical ectopic pregnancy.子宫动脉栓塞术治疗宫颈异位妊娠
Radiol Case Rep. 2015 Oct 9;10(4):72-5. doi: 10.1016/j.radcr.2015.08.004. eCollection 2015 Dec.
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Advanced extrauterine pregnancy: diagnostic and therapeutic challenges.晚期宫外妊娠:诊断与治疗挑战
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Management of primary abdominal pregnancy: twelve years of experience in a medical centre.原发性腹腔妊娠的管理:一家医疗中心的十二年经验
Acta Obstet Gynecol Scand. 2007;86(9):1058-62. doi: 10.1080/00016340701434476.
8
A report of four cases of caesarean scar pregnancy in a period of 12 months.一份关于12个月内4例剖宫产瘢痕妊娠病例的报告。
Hong Kong Med J. 2007 Apr;13(2):141-3.
9
Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases.异位妊娠的发病部位:一项基于10年1800例病例的人群研究。
Hum Reprod. 2002 Dec;17(12):3224-30. doi: 10.1093/humrep/17.12.3224.