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原发性脐尿管腺癌经手术及术后放化疗有效治疗:病例报告并文献复习

Primary urachal adenocarcinoma treated effectively with surgery and post operative chemoradiation therapy: Case Report with review of the literature.

作者信息

Kouhen Fadila, Chihabeddine Meriem, Dahbi Zineb, Benali Imane, Damou Meriem, Benslima Nejwa, Haddat Abdeljalil, Errafiy Nadia, Mahi Mohammed, Rabii Radouane

机构信息

Department of Radiotherapy, Mohammed VI University of Health Sciences(UM6SS), International University Hospital Sheikh Khalifa, Casablanca, Morocco.

Department of Medical Oncology, Mohammed VI University of Health Sciences(UM6SS), International University Hospital Sheikh Khalifa, Casablanca, Morocco.

出版信息

Radiol Case Rep. 2021 Jun 16;16(8):2252-2255. doi: 10.1016/j.radcr.2021.04.084. eCollection 2021 Aug.

DOI:10.1016/j.radcr.2021.04.084
PMID:34188738
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8220099/
Abstract

Urachal carcinomas is a rare and aggressive tumor, accounting for less than 1% of all bladder cancers. We report a case of a 32-year-old man, with no past medical history, complaining of a total hematuria. The abdominal computed tomography scan revealed an exophytic mass of 3 cm on the dome of the bladder, extending to the urachus. The computed tomography scan of chest, abdomen and pelvis did not show neither regional or distant metastasis. Partial Cystectomy with umbilectomy was performed. Histopathology was in favor of urachal adenocarcinoma, classed pT3a, based on Sheldon's staging system, pT2b based on Mayo system, and pT2 based on Ontario system.

摘要

脐尿管癌是一种罕见的侵袭性肿瘤,占所有膀胱癌的比例不到1%。我们报告一例32岁男性病例,该患者无既往病史,主诉全程血尿。腹部计算机断层扫描显示膀胱顶部有一个3厘米的外生性肿块,延伸至脐尿管。胸部、腹部和骨盆的计算机断层扫描未显示区域或远处转移。行膀胱部分切除术及脐切除术。组织病理学结果支持脐尿管腺癌,根据谢尔登分期系统分类为pT3a,根据梅奥系统分类为pT2b,根据安大略系统分类为pT2。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbd5/8220099/621d8cf48144/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbd5/8220099/621d8cf48144/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbd5/8220099/621d8cf48144/gr1.jpg

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本文引用的文献

1
Management of urachal cancer: A consensus statement by the Canadian Urological Association and Genitourinary Medical Oncologists of Canada.脐尿管癌的管理:加拿大泌尿外科协会和加拿大泌尿生殖系统医学肿瘤学家的共识声明
Can Urol Assoc J. 2020 Mar;14(3):E57-E64. doi: 10.5489/cuaj.5946. Epub 2019 Jul 23.
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National Incidence, Management and Survival of Urachal Carcinoma.脐尿管癌的全国发病率、治疗及生存情况
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脐尿管源性上皮性肿瘤的病理诊断与分类的进展
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Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation.脐尿管癌:24例临床病理分析及预后相关性研究
Am J Surg Pathol. 2009 May;33(5):659-68. doi: 10.1097/PAS.0b013e31819aa4ae.
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