妊娠期间因昂丹司琼导致的中毒性表皮坏死松解症且预后良好：一例病例报告及文献综述
Toxic Epidermal Necrolysis in Pregnancy due to Ondansetron with a Favorable Outcome: A Case Report and Review of the Literature.
作者信息
Shakoei Safoura, Daneshpazhooh Maryam, Nasimi Maryam, Hamzelou Shahin
机构信息
Drs. Shakoei and Hamzelou are with the Department of Dermatology at Imam Khomeini Hospital, Tehran University of Medical Sciences in Tehran, Iran.
Drs. Daneshpazhooh and Nasimi are with the Department of Dermatology at Razi Hospital, Tehran University of Medical Sciences in Tehran, Iran.
出版信息
J Clin Aesthet Dermatol. 2021 May;14(5):46-49. Epub 2021 May 1.
Abstract
Toxic epidermal necrolysis (TEN) is an uncommon, life-threatening hypersensitivity drug reaction with a high mortality rate that involves the skin and mucous membranes. Most reported cases involving pregnant patients were seen in those with human immunodeficiency virus. Here, we discuss a 21-year-old Iranian woman who presented at 18 weeks' gestation with extensive TEN following the administration of ondansetron with no any other risk factors.
摘要
中毒性表皮坏死松解症（TEN）是一种罕见的、危及生命的超敏反应性药物不良反应，死亡率高，累及皮肤和黏膜。大多数报道的涉及孕妇的病例见于感染人类免疫缺陷病毒的患者。在此，我们讨论一名21岁的伊朗女性，她在妊娠18周时因使用昂丹司琼后出现广泛的中毒性表皮坏死松解症，且无任何其他风险因素。
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